Description

2-Oxa-8-Azaspiro[4.5]Decan-4-One, Hydrochloride (1:1) is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel active pharmaceutical ingredients (APIs) targeting central nervous system and other therapeutic areas. It is primarily sought by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in innovative drug discovery programs.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those with spirocyclic architectures.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic agents.
• API Development: Employed in the research-scale preparation of active pharmaceutical ingredients, particularly for neurological targets.
• Chemical Biology Probes: Utilized in the development of tool compounds for studying biological pathways and target validation.
• Academic Research: A valuable reagent for universities and research institutes exploring new synthetic methodologies and heterocyclic chemistry.

Basic Information

Product Name	2-Oxa-8-Azaspiro[4.5]Decan-4-One, Hydrochloride (1:1)
CAS No.	2306270-36-8
Molecular Formula	C8H14ClNO2
Molecular Weight	191.66 g/mol
Synonyms	2-Oxa-8-azaspiro[4.5]decan-4-one hydrochloride; 8-Aza-2-oxaspiro[4.5]decan-4-one hydrochloride; Spiro[4.5]decan-4-one, 2-oxa-8-aza-, hydrochloride; 2-Oxa-8-azaspiro[4.5]decan-4-one HCl; 2306270-36-8; 2-Oxa-8-azaspiro[4.5]decan-4-one monohydrochloride
EINECS	Contact for details

Quality Control

Our 2-Oxa-8-Azaspiro[4.5]Decan-4-One, Hydrochloride (1:1) is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. We provide comprehensive analytical data, including HPLC purity, NMR, and mass spectrometry confirmation. A detailed Certificate of Analysis (COA) is supplied with each batch to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.