Description

2-Azaspiro[3.5]Nonane-7-Acetic Acid, 2-[(1,1-Dimethylethoxy)Carbonyl]- is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic and protected amino acid structure. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel drug candidates targeting complex biological pathways. It is primarily utilized by pharmaceutical R&D laboratories and fine chemical manufacturers engaged in the production of sophisticated active pharmaceutical ingredients (APIs) and bioactive molecules.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel drug candidates, especially those requiring constrained, spirocyclic architectures for enhanced binding affinity and metabolic stability.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical space for central nervous system (CNS), oncology, and anti-infective therapeutic areas.
• Peptidomimetic Synthesis: The protected amino acid moiety makes it valuable for constructing non-natural amino acids and peptide mimics with improved pharmacological properties.
• Chemical Biology Probes: Employed in the development of specialized molecular probes and tools for studying enzyme mechanisms and protein-protein interactions.
• Custom Synthesis & Contract Manufacturing: A critical starting material for custom synthesis projects and contract research organizations (CROs/CMOs) producing high-value, low-volume specialty chemicals.

Basic Information

Product Name	2-Azaspiro[3.5]Nonane-7-Acetic Acid, 2-[(1,1-Dimethylethoxy)Carbonyl]-
CAS No.	2306261-01-6
Molecular Formula	C14H23NO4
Molecular Weight	269.34 g/mol
Synonyms	Boc-2-Azaspiro[3.5]nonane-7-acetic acid; 2-[(tert-Butoxycarbonyl)amino]spiro[3.5]nonane-7-acetic acid; tert-Butyl 2-azaspiro[3.5]nonane-7-acetate-2-carboxylate; 2-(Boc-amino)spiro[3.5]nonane-7-acetic acid; 2-Azaspiro[3.5]nonane-7-acetic acid, N-Boc-protected; N-Boc-2-azaspiro[3.5]nonane-7-acetic acid; 2306261-01-6; Boc-Spiro[3.5]nonane-AA-OH
EINECS	Contact for details

Quality Control

Our 2-Azaspiro[3.5]Nonane-7-Acetic Acid, 2-[(1,1-Dimethylethoxy)Carbonyl]- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing purity, impurities, and physical characteristics is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere such as nitrogen or argon to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.