Description

1-(2-Methoxy-1,1-Dimethyl-Ethyl)Pyrazole-4-Boronic Acid Pinacol Ester is a high-purity, advanced pharmaceutical intermediate and versatile building block for organic synthesis. Its core value lies in enabling efficient Suzuki-Miyaura cross-coupling reactions, a critical step in constructing complex molecules for active pharmaceutical ingredients (APIs). This compound is essential for R&D chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries seeking to develop new drug candidates and specialty chemicals. CAS No. 2304635-54-7.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates, particularly in medicinal chemistry programs targeting various therapeutic areas.
• Suzuki-Miyaura Cross-Coupling Reactions: Serves as a critical boron-containing coupling partner for forming carbon-carbon bonds between aromatic and heteroaromatic systems.
• Agrochemical Research: Used in the development of new pesticides, herbicides, and fungicides by providing a functionalized pyrazole scaffold.
• Material Science & OLED Development: Employed in the synthesis of organic electronic materials, including ligands for metal-organic frameworks (MOFs) and emissive layers for OLEDs.
• Chemical Biology & Probe Synthesis: Facilitates the creation of molecular probes and labeled compounds for biochemical and diagnostic applications.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring specific boronic ester functionalities.

Basic Information

Product Name	1-(2-Methoxy-1,1-Dimethyl-Ethyl)Pyrazole-4-Boronic Acid Pinacol Ester
CAS No.	2304635-54-7
Molecular Formula	C15H27BN2O3
Molecular Weight	294.20 g/mol
Synonyms	4-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)-1-(2-methoxy-2-methylpropyl)-1H-pyrazole; 1-(2-Methoxy-2-methylpropyl)-4-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)-1H-pyrazole; 1-(2-Methoxy-1,1-dimethylethyl)-1H-pyrazole-4-boronic acid pinacol ester; 1-(2-Methoxy-2-methylpropyl)-1H-pyrazole-4-boronic acid pinacol ester; 1-(Methoxymethyl-1-methylethyl)pyrazole-4-boronic acid pinacol ester; Pyrazole-4-boronic acid pinacol ester, 1-(2-methoxy-1,1-dimethylethyl)-; CAS 2304635-54-7
EINECS	Contact for details

Quality Control

Our 1-(2-Methoxy-1,1-Dimethyl-Ethyl)Pyrazole-4-Boronic Acid Pinacol Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. Certificates of Analysis (COA) with detailed specifications are provided for every shipment to guarantee batch-to-batch consistency and support your regulatory and R&D requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, containers must be kept tightly sealed and under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with reference structure
Purity (HPLC)	≥ 97.0% (Area %)
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.