Description

1,3,2-Dioxaborolane, 2-[3-(Difluoromethyl)-5-Methoxyphenyl]-4,4,5,5-Tetramethyl- is a high-purity, advanced boronic ester building block designed for sophisticated organic synthesis. This compound matters as a critical intermediate for constructing complex molecules, particularly in the development of new active pharmaceutical ingredients (APIs) and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced materials industries seeking to introduce the versatile boronic ester functional group into target structures.

Application

• Pharmaceutical Intermediate: A key precursor in Suzuki-Miyaura cross-coupling reactions for the synthesis of novel drug candidates, especially in oncology and CNS therapeutic areas.
• Agrochemical Synthesis: Used in the research and development of next-generation herbicides, fungicides, and insecticides requiring specific aryl-boronate motifs.
• Material Science Research: Serves as a monomer or functionalization agent in the creation of organic electronic materials, such as OLEDs and organic semiconductors.
• Chemical Biology Probes: Employed in the synthesis of bioconjugates and molecular probes for diagnostic and biochemical research applications.
• Process Chemistry: Utilized in route scouting and scale-up for the efficient, large-scale production of fine chemicals and complex organic molecules.

Basic Information

Product Name	1,3,2-Dioxaborolane, 2-[3-(Difluoromethyl)-5-Methoxyphenyl]-4,4,5,5-Tetramethyl-
CAS No.	2304635-41-2
Molecular Formula	C14H19BF2O3
Molecular Weight	284.11 g/mol
Synonyms	2-(3-(Difluoromethyl)-5-methoxyphenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; [3-(Difluoromethyl)-5-methoxyphenyl]boronic acid pinacol ester; 3-(Difluoromethyl)-5-methoxybenzeneboronic acid pinacol ester; 3-(Difluoromethyl)-5-methoxyphenylboronic acid pinacol ester; (3-(Difluoromethyl)-5-methoxyphenyl)pinacolboronate; Difluoromethyl-methoxyphenyl pinacol boronate; CAS 2304635-41-2
EINECS	Contact for details

Quality Control

Our 1,3,2-Dioxaborolane, 2-[3-(Difluoromethyl)-5-Methoxyphenyl]-4,4,5,5-Tetramethyl- is manufactured under strict quality management systems to ensure batch-to-batch consistency and high purity suitable for demanding synthetic applications. Each lot undergoes rigorous analytical testing, including NMR, HPLC, and GC analysis. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled under an inert atmosphere (e.g., nitrogen or argon) when possible to maintain stability and prevent hydrolysis. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥97.0%
Purity (GC)	≥97.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.