Description

Propanoic Acid, 3-(2-Iodoethoxy)-, 1,1-Dimethylethyl Ester is a specialized iodinated organic building block of significant interest in advanced synthetic chemistry. Its core value lies in its unique molecular architecture, which combines a protected carboxylic acid group with an iodoether functionality, making it a versatile intermediate for constructing complex molecules. This compound is primarily needed by research and development chemists in the pharmaceutical and agrochemical industries for applications in medicinal chemistry and material science.

Application

• Pharmaceutical Intermediate: Serves as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for introducing ether-linked side chains or for further functionalization via the iodine atom.
• Agrochemical Synthesis: Used in the research and development of new herbicides, fungicides, and plant growth regulators where its specific structure can contribute to biological activity.
• Material Science Research: Acts as a monomer or precursor for synthesizing specialized polymers and advanced organic materials with tailored properties.
• Cross-Coupling Reactions: The iodine atom makes it a suitable substrate for various palladium-catalyzed cross-coupling reactions (e.g., Suzuki, Sonogashira) to form carbon-carbon bonds.
• Protecting Group Strategy: The tert-butyl ester group provides a protected carboxylic acid functionality that can be deprotected under mild acidic conditions in multi-step syntheses.
• Chemical Biology Probes: Utilized in the development of molecular probes and labeled compounds for biochemical and diagnostic research applications.

Basic Information

Product Name	Propanoic Acid, 3-(2-Iodoethoxy)-, 1,1-Dimethylethyl Ester
CAS No.	2296723-16-3
Molecular Formula	C9H17IO3
Molecular Weight	300.14 g/mol
Synonyms	tert-Butyl 3-(2-iodoethoxy)propanoate; 1,1-Dimethylethyl 3-(2-iodoethoxy)propanoate; 3-(2-Iodoethoxy)propanoic Acid tert-Butyl Ester; Propanoic acid, 3-(2-iodoethoxy)-, 1,1-dimethylethyl ester; tert-Butyl 3-(2-iodoethoxy)propionate; 2-(2-tert-Butoxy-2-oxoethoxy)ethyl iodide
EINECS	Contact for details

Quality Control

Our Propanoic Acid, 3-(2-Iodoethoxy)-, 1,1-Dimethylethyl Ester is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all relevant specifications. Our quality systems are designed to support cGMP and ISO standards for reliable and consistent supply to the pharmaceutical and fine chemical industries.

Storage

Preserve in a tightly closed container, protected from light. Store under an inert atmosphere (e.g., nitrogen or argon) in a cool, dry, and well-ventilated place. Recommended long-term storage temperature is 2-8°C. Allow the container to reach ambient temperature before opening to minimize moisture ingress.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.