Description

2-(6-Bromo-8-Fluoro-3-Quinolyl)Ethoxy-tert-Butyl-Dimethyl-Silane is a high-value, protected intermediate crucial for advanced organic synthesis. This compound is specifically engineered to serve as a key building block in the development of complex pharmaceutical and agrochemical agents. It is primarily required by R&D chemists and process development scientists in the life sciences sector for constructing novel quinoline-based molecular architectures.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other targeted therapies.
• Agrochemical Research: Used in the development of new herbicides and fungicides that leverage the quinoline scaffold for enhanced biological activity.
• Material Science: Serves as a specialized monomer or functionalizing agent for creating advanced polymers with specific optical or electronic properties.
• Chemical Biology: Employed in the synthesis of molecular probes and labeled compounds for diagnostic and research applications.
• Academic & Industrial R&D: A versatile reagent for methodology development and exploring new synthetic routes in heterocyclic chemistry.

Basic Information

Product Name	2-(6-Bromo-8-Fluoro-3-Quinolyl)Ethoxy-tert-Butyl-Dimethyl-Silane
CAS No.	2288708-54-1
Molecular Formula	C₁₉H₂₇BrFNO₃Si
Molecular Weight	428.42 g/mol
Synonyms	2-(6-Bromo-8-fluoroquinolin-3-yl)ethoxy-tert-butyldimethylsilane; 6-Bromo-8-fluoro-3-[2-[(tert-butyldimethylsilyl)oxy]ethyl]quinoline; TBDMS Ether of 2-(6-Bromo-8-Fluoro-3-Quinolyl)Ethanol; 2288708-54-1; tert-Butyl((2-(6-bromo-8-fluoroquinolin-3-yl)ethoxy)dimethylsilane; (6-Bromo-8-fluoro-3-quinolyl)ethyl tert-butyldimethylsilyl ether; 3-(2-((tert-Butyldimethylsilyl)oxy)ethyl)-6-bromo-8-fluoroquinoline
EINECS	Contact for details

Quality Control

Our 2-(6-Bromo-8-Fluoro-3-Quinolyl)Ethoxy-tert-Butyl-Dimethyl-Silane is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and GC-MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with customer specifications and industry best practices for advanced intermediates.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.