Description

(7-Oxaspiro[3.5]Nonan-2-Yl)Methanamine Hydrochloride is a high-purity, advanced pharmaceutical intermediate characterized by its unique spirocyclic amine structure. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily utilized by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries seeking to develop new therapeutic agents.

Application

• Pharmaceutical Intermediate: A key chiral building block for the synthesis of novel drug candidates targeting central nervous system (CNS) disorders, metabolic diseases, and anti-infective agents.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization programs due to its constrained spirocyclic scaffold, which can improve metabolic stability and receptor binding affinity.
• Process Chemistry & Scale-Up: Serves as a starting material or intermediate in the development of robust, scalable synthetic routes for potential APIs under Good Manufacturing Practice (GMP) conditions.
• Bioconjugation & Probe Development: The primary amine functionality, protected as its hydrochloride salt, is suitable for conjugation reactions in the development of chemical probes, diagnostic tools, or targeted drug delivery systems.
• Academic & Institutional R&D: Employed in university and research institute laboratories for exploratory synthetic chemistry and the development of new methodologies involving complex amine derivatives.
• Custom Synthesis & Contract Manufacturing: A critical material for fine chemical companies offering custom synthesis services for virtual pharma and biotech clients.

Basic Information

Product Name	(7-Oxaspiro[3.5]Nonan-2-Yl)Methanamine Hydrochloride
CAS No.	2250243-27-5
Molecular Formula	C9H18ClNO
Molecular Weight	191.70 g/mol
Synonyms	2-(Aminomethyl)-7-oxaspiro[3.5]nonane hydrochloride; 7-Oxaspiro[3.5]nonane-2-methanamine hydrochloride; (7-Oxaspiro[3.5]nonan-2-yl)methanamine HCl; 2-(Aminomethyl)-7-oxaspiro[3.5]nonane HCl; 7-Oxaspiro[3.5]nonan-2-ylmethylamine hydrochloride; Spiro[3.5]nonan-2-ylmethanamine, 7-oxa-, hydrochloride; (2-Aminomethyl-7-oxaspiro[3.5]nonane) hydrochloride
EINECS	Contact for details

Quality Control

Every batch of (7-Oxaspiro[3.5]Nonan-2-Yl)Methanamine Hydrochloride is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the material meets the high-purity standards required for advanced pharmaceutical R&D. A detailed Certificate of Analysis (COA) is supplied with each shipment, reporting results from advanced analytical techniques including HPLC, NMR, and MS to confirm identity, purity, and impurity profile.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place. Due to its hygroscopic nature, the container should be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption. Recommended long-term storage at 2-8°C for optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	< 10 ppm
Residual Solvents (GC)	Complies with ICH Q3C

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.