Description

4-[2-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxymethyl]-Benzonitrile is a high-value, advanced pharmaceutical intermediate and building block for organic synthesis. This compound matters for its role as a key precursor in cross-coupling reactions, enabling the efficient construction of complex molecules. It is primarily needed by researchers and manufacturers in the pharmaceutical, agrochemical, and material science industries for developing new active ingredients and functional materials.

Application

• Pharmaceutical Intermediate: A critical building block in the synthesis of active pharmaceutical ingredients (APIs) via Suzuki-Miyaura cross-coupling reactions.
• Agrochemical Research: Used in the development of novel herbicides, fungicides, and insecticides requiring specific aryl-aryl linkages.
• Material Science: Serves as a monomer or precursor for creating advanced organic electronic materials, such as OLEDs and organic semiconductors.
• Chemical Synthesis: An essential reagent for constructing biaryl and heterobiaryl structures in complex natural product synthesis and medicinal chemistry.
• Ligand & Catalyst Development: Employed in the research and preparation of novel ligands and organometallic catalysts.
• Life Science Tools: Used in the development of molecular probes, fluorescent tags, and other diagnostic reagents.

Basic Information

Product Name	4-[2-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxymethyl]-Benzonitrile
CAS No.	2246880-79-3
Molecular Formula	C20H22BNO3
Molecular Weight	335.21 g/mol
Synonyms	2-(4-(Cyanobenzyl)oxy)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; 4-((2-(4,4,5,5-Tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy)methyl)benzonitrile; Benzonitrile, 4-[[2-(4,4,5,5-tetramethyl-1,3,2-dioxaborolan-2-yl)phenoxy]methyl]-; Boronic acid, B-[2-[[(4-cyanophenyl)methyl]oxy]phenyl]-4,4,5,5-tetramethyl-1,3,2-dioxaborolane ester
EINECS	Contact for details

Quality Control

Our 4-[2-(4,4,5,5-Tetramethyl-[1,3,2]Dioxaborolan-2-Yl)-Phenoxymethyl]-Benzonitrile is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and LC-MS, to ensure high purity and consistency. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment to support your quality assurance and regulatory needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and must be handled under an inert atmosphere (e.g., nitrogen or argon) for long-term storage and to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.