Description

2-Bromo-5-Chloro-1H-Pyrrolo[2,3-C]Pyridine is a high-purity halogenated heterocyclic building block of significant importance in modern organic synthesis. This compound matters because it serves as a critical intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. It is primarily needed by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and agrochemical industries for lead optimization and the synthesis of active pharmaceutical ingredients (APIs).

Application

• Pharmaceutical Intermediate: A key synthon for the synthesis of kinase inhibitors and other small-molecule drug candidates targeting various therapeutic areas.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its halogenated pyrrolopyridine core.
• Material Science: Serves as a precursor for organic electronic materials, such as ligands for OLEDs or conductive polymers.
• Chemical Biology: Employed as a molecular probe or a tagged building block in proteomics and bio-conjugation studies.
• Academic & Contract Research: Utilized in university and CRO laboratories for methodological development and exploring new chemical spaces.
• Custom Synthesis: A starting point for the contract manufacturing of specialized, high-value fine chemicals for client-specific projects.

Basic Information

Product Name	2-Bromo-5-Chloro-1H-Pyrrolo[2,3-C]Pyridine
CAS No.	2231674-73-8
Molecular Formula	C7H4BrClN2
Molecular Weight	231.48 g/mol
Synonyms	2-Bromo-5-chloro-1H-pyrrolo[2,3-c]pyridine; 1H-Pyrrolo[2,3-c]pyridine, 2-bromo-5-chloro-; 5-Chloro-2-bromo-1H-pyrrolo[2,3-c]pyridine; 2-Bromo-5-chloro-7-azaindole; 5-Chloro-2-bromo-7-azaindole; Bromo-chloro-pyrrolopyridine; Azaindole derivative CAS 2231674-73-8
EINECS	Contact for details

Quality Control

Our 2-Bromo-5-Chloro-1H-Pyrrolo[2,3-C]Pyridine is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high chemical purity and identity confirmation. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all specified parameters. Our quality commitment aligns with cGMP principles for advanced pharmaceutical intermediates, ensuring traceability and consistency for critical R&D and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This material is light-sensitive (store away from light). Keep the container tightly sealed in a dry environment to prevent moisture absorption. Store away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Single Unknown Impurity (HPLC)	≤ 1.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.