Description

trans-2-(3-(Trifluoromethyl)Pyridin-2-Yl)Cyclopropane-1-Carboxylic Acid CAS NO 2227694-59-7 is a high-value, multifunctional organic building block characterized by its cyclopropane ring and trifluoromethylpyridine moiety. This compound is essential for medicinal chemistry research and development, offering a unique structural motif for modulating the physicochemical properties of lead candidates. It is primarily utilized by pharmaceutical R&D teams and fine chemical manufacturers engaged in the synthesis of novel active pharmaceutical ingredients (APIs) and agrochemicals.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the synthesis of drug candidates, particularly those targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Synthesis: Used in the development of advanced pesticides and herbicides, where the trifluoromethyl group enhances biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a sophisticated ligand precursor in asymmetric catalysis and metal-organic frameworks (MOFs).
• Material Science Research: Employed in the creation of specialty polymers and advanced organic electronic materials due to its rigid, aromatic structure.
• Chemical Biology Probes: Utilized as a scaffold for developing molecular probes to study enzyme function and protein-ligand interactions.

Basic Information

Product Name	trans-2-(3-(Trifluoromethyl)Pyridin-2-Yl)Cyclopropane-1-Carboxylic Acid
CAS No.	2227694-59-7
Molecular Formula	C10H8F3NO2
Molecular Weight	231.17 g/mol
Synonyms	2-(3-(Trifluoromethyl)pyridin-2-yl)cyclopropane-1-carboxylic acid; trans-2-[3-(Trifluoromethyl)-2-pyridyl]cyclopropanecarboxylic Acid; (1R,2S)-rel-2-[3-(Trifluoromethyl)-2-pyridinyl]cyclopropanecarboxylic Acid; (1S,2R)-rel-2-[3-(Trifluoromethyl)-2-pyridinyl]cyclopropanecarboxylic Acid; 2-(3-Trifluoromethyl-pyridin-2-yl)-cyclopropanecarboxylic acid; 2227694-59-7; 2-(3-(Trifluoromethyl)pyridin-2-yl)cyclopropanecarboxylic acid
EINECS	Contact for details

Quality Control

Our production of trans-2-(3-(Trifluoromethyl)Pyridin-2-Yl)Cyclopropane-1-Carboxylic Acid adheres to stringent quality management protocols. Every batch undergoes comprehensive analytical characterization, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) detailing all specifications are provided and can be tailored to meet specific client or regulatory requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). Keep away from strong acids and organic solvents. The container must be kept tightly closed in a dry environment to minimize moisture exposure.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms
Identification (IR)	Conforms
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.