Description

2-(Hydroxy(Pyridin-4-Yl)Methyl)-5,6-Dimethoxy-2,3-Dihydro-1H-Inden-1-One is a high-purity, advanced pharmaceutical intermediate characterized by its complex indanone-pyridine hybrid structure. This compound is of significant value for research and development in medicinal chemistry, particularly for its potential role as a key building block in synthesizing novel active pharmaceutical ingredients (APIs). It is primarily needed by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing new therapeutic agents, especially in areas like neurology and oncology.

Application

• Pharmaceutical Intermediate: Serves as a critical precursor in the multi-step synthesis of novel drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used as a scaffold or building block for structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• API Development: Integral in the development and scale-up processes for new Active Pharmaceutical Ingredients (APIs), particularly those with complex heterocyclic architectures.
• Biochemical Tool Compound: May be utilized in biochemical assays to study enzyme inhibition or receptor modulation for target validation.
• Contract Synthesis: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects requiring high-purity, specialized intermediates.

Basic Information

Product Name	2-(Hydroxy(Pyridin-4-Yl)Methyl)-5,6-Dimethoxy-2,3-Dihydro-1H-Inden-1-One
CAS No.	2227606-37-1
Molecular Formula	C₁₇H₁₇NO₄
Molecular Weight	299.32 g/mol
Synonyms	5,6-Dimethoxy-2-[(pyridin-4-yl)(hydroxy)methyl]-2,3-dihydro-1H-inden-1-one; 2,3-Dihydro-5,6-dimethoxy-2-[(4-pyridinyl)hydroxymethyl]-1H-inden-1-one; 2-(Hydroxy(pyridin-4-yl)methyl)-5,6-dimethoxyindan-1-one; 1H-Inden-1-one, 2,3-dihydro-5,6-dimethoxy-2-[(4-pyridinyl)hydroxymethyl]-; (5,6-Dimethoxy-1-oxo-2,3-dihydro-1H-inden-2-yl)(pyridin-4-yl)methanol
EINECS	Contact for details

Quality Control

Our 2-(Hydroxy(Pyridin-4-Yl)Methyl)-5,6-Dimethoxy-2,3-Dihydro-1H-Inden-1-One is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, ensuring reliability for your most demanding research and development projects.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). This material is light-sensitive and should be handled under appropriate conditions to maintain stability. Keep away from incompatible materials.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.