Description

Cyclopropanecarboxamide, 1-(2-Fluorophenyl)-n-[1-(2-Fluoro-4-Pyridinyl)-1H-Pyrazol-3-Yl]- is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active pharmaceutical ingredients (APIs). This compound is critical for research and development in medicinal chemistry, offering a sophisticated building block for creating targeted therapeutic agents. It is primarily utilized by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers focused on developing next-generation drug candidates.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates targeting various disease pathways.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new therapeutic entities.
• API Development: Serves as a critical precursor in the multi-step synthesis of complex Active Pharmaceutical Ingredients (APIs).
• Biochemical Research: Employed as a tool compound or probe in biochemical assays to study specific biological interactions.
• Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for custom synthesis projects.
• Preclinical Development: Used in the production of materials required for preclinical toxicology and pharmacokinetic studies.

Basic Information

Product Name	Cyclopropanecarboxamide, 1-(2-Fluorophenyl)-n-[1-(2-Fluoro-4-Pyridinyl)-1H-Pyrazol-3-Yl]-
CAS No.	2227482-41-7
Molecular Formula	C18H13F2N5O
Molecular Weight	353.33 g/mol
Synonyms	1-(2-Fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]cyclopropanecarboxamide; 1-(2-Fluorophenyl)-N-(1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl)cyclopropanecarboxamide; Cyclopropanecarboxamide, 1-(2-fluorophenyl)-N-[1-(2-fluoro-4-pyridinyl)-1H-pyrazol-3-yl]-; UNII-6G6W9F0F6T; 6G6W9F0F6T; 2227482-41-7; CHEMBL3186669; AKOS040759946
EINECS	Contact for details

Quality Control

Our Cyclopropanecarboxamide, 1-(2-Fluorophenyl)-n-[1-(2-Fluoro-4-Pyridinyl)-1H-Pyrazol-3-Yl]- is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where applicable, supporting its use in regulated pharmaceutical development.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This product is hygroscopic (moisture-sensitive) and should be handled in a dry environment to prevent degradation. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.