Description

2,9-Diazaspiro[5.5]undecane dihydrochloride is a high-purity, bicyclic diamine hydrochloride salt of significant interest in advanced organic synthesis. This compound serves as a crucial pharmacophore and versatile building block for the development of novel active pharmaceutical ingredients (APIs) and other fine chemicals. It is primarily utilized by pharmaceutical R&D laboratories and contract research and manufacturing organizations (CROs/CMOs) engaged in drug discovery and process chemistry.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the development of new therapeutic agents, particularly in central nervous system (CNS) and metabolic disorder research.
• Ligand Synthesis: Used to construct complex chelating ligands for catalysis and metal-organic frameworks (MOFs).
• Chemical Biology Probe Development: Employed in the synthesis of molecular probes for studying enzyme function and biological pathways.
• Agrochemical Research: Acts as a building block for novel crop protection agents and pesticides.
• Academic & Industrial R&D: Serves as a valuable scaffold in medicinal chemistry programs for structure-activity relationship (SAR) studies.
• Custom Synthesis: A starting material for the contract manufacturing of proprietary compounds and specialty chemicals.

Basic Information

Product Name	2,9-Diazaspiro[5.5]undecane dihydrochloride
CAS No.	2227206-72-4
Molecular Formula	C9H20Cl2N2
Molecular Weight	227.18 g/mol
Synonyms	2,9-Diazaspiro[5.5]undecane, 2HCl; 2,9-Diazaspiro[5.5]undecane hydrochloride; 2,9-Diazaspiro[5.5]undecane dihydrochloride salt; Spiro[5.5]undecane-2,9-diamine dihydrochloride; 1,4-Diazaspiro[5.5]undecane dihydrochloride (common numbering variant); 2,9-Diaza-spiro[5.5]undecane dihydrochloride; Bicyclic diamine hydrochloride
EINECS	Contact for details

Quality Control

Our 2,9-Diazaspiro[5.5]undecane dihydrochloride is manufactured under a strict quality management system. Each batch undergoes comprehensive analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with every shipment, confirming compliance with agreed specifications. We support development and commercial projects requiring material suitable for use under cGMP guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed after opening to prevent moisture absorption, which can affect stability and handling properties.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.