Description

tert-Butyl 7-Oxa-6-Thia-5-Azaspiro[3.4]Octane-5-Carboxylate 6,6-Dioxide is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic sulfonamide scaffold. This compound is specifically engineered to serve as a critical building block in modern drug discovery, enabling the synthesis of novel bioactive molecules with enhanced properties. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in areas requiring complex heterocyclic chemistry.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel Active Pharmaceutical Ingredients (APIs) targeting a range of therapeutic areas.
• Proteolysis Targeting Chimera (PROTAC) Development: Utilized as a component in the linker or warhead design for targeted protein degradation platforms.
• Medicinal Chemistry Research: Serves as a versatile scaffold for constructing compound libraries in high-throughput screening and structure-activity relationship (SAR) studies.
• Sulfonamide-Based Drug Discovery: Provides the core sulfonamide-dioxide moiety essential for developing molecules with potential enzyme inhibitory activity.
• Chemical Biology Probes: Used in the creation of specialized molecular tools for studying biological pathways and protein function.
• Agrochemical Research: Potential intermediate for developing new crop protection agents with novel modes of action.

Basic Information

Product Name	tert-Butyl 7-Oxa-6-Thia-5-Azaspiro[3.4]Octane-5-Carboxylate 6,6-Dioxide
CAS No.	2227204-96-6
Molecular Formula	C10H17NO5S
Molecular Weight	263.31 g/mol
Synonyms	5-[(tert-Butoxy)carbonyl]-7-oxa-6-thia-5-azaspiro[3.4]octane 6,6-dioxide; tert-Butyl 5-azaspiro[3.4]octane-5-carboxylate 6,6-dioxide (7-oxa-6-thia-); 7-Oxa-6-thia-5-azaspiro[3.4]octane-5-carboxylic acid, 1,1-dimethylethyl ester, 6,6-dioxide; Spirocyclic Sulfonamide Ester; Boc-Protected Spirocyclic Sulfamoyl Derivative; tert-Butyl 7-oxa-6-thia-5-azaspiro[3.4]octane-5-carboxylate S,S-dioxide
EINECS	Contact for details

Quality Control

Our tert-Butyl 7-Oxa-6-Thia-5-Azaspiro[3.4]Octane-5-Carboxylate 6,6-Dioxide is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing to ensure high purity and consistency, meeting the stringent requirements for pharmaceutical R&D. Comprehensive Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with each shipment to support your regulatory and research needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (typically 15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.