Description

tert-Butyl 5-Fluoro-2,7-Diazaspiro[3.5]Nonane-2-Carboxylate Hydrochloride is a high-purity, advanced pharmaceutical intermediate designed for modern drug discovery and development. This compound serves as a critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly those targeting central nervous system and oncological pathways. It is essential for medicinal chemistry research and process development teams in pharmaceutical and biotechnology companies seeking to develop new therapeutic entities.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and oncology targets.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to develop new chemical entities.
• Process Chemistry Development: Serves as a critical starting material for scaling up API synthesis under Good Manufacturing Practice (GMP) conditions.
• Proteolysis Targeting Chimera (PROTAC) Development: A valuable component for constructing bifunctional molecules used in targeted protein degradation strategies.
• Chemical Biology Probes: Utilized in the creation of tool compounds for investigating biological pathways and target validation.
• Custom Synthesis Projects: Employed by contract research and manufacturing organizations (CROs/CMOs) for client-specific synthesis projects.

Basic Information

Item	Details
Product Name	tert-Butyl 5-Fluoro-2,7-Diazaspiro[3.5]Nonane-2-Carboxylate Hydrochloride
CAS No.	2227204-85-3
Molecular Formula	C12H22FN2O2 • HCl
Molecular Weight	290.78 g/mol
Synonyms	5-Fluoro-2,7-diazaspiro[3.5]nonane-2-carboxylic acid tert-butyl ester hydrochloride; tert-Butyl 5-fluoro-2,7-diazaspiro[3.5]nonane-2-carboxylate HCl; 2,7-Diazaspiro[3.5]nonane-2-carboxylic acid, 5-fluoro-, 1,1-dimethylethyl ester, hydrochloride; 2227204-85-3; 5-Fluoro-2,7-diazaspiro[3.5]nonane-2-carboxylate tert-butyl ester hydrochloride; tert-Butyl 5-fluoro-2,7-diazaspiro[3.5]nonane-2-carboxylate hydrochloride salt
EINECS	Contact for details

Quality Control

Our tert-Butyl 5-Fluoro-2,7-Diazaspiro[3.5]Nonane-2-Carboxylate Hydrochloride is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity suitable for research and development. Our products undergo rigorous quality testing to ensure compliance with industry standards. Certificates of Analysis (COA) are available upon request, detailing key parameters such as assay, purity, and identity.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and should be handled under dry conditions or an inert atmosphere to prevent degradation. Keep the container tightly sealed when not in use.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Assay (HPLC)	≥ 98.0%
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.