Description

tert-Butyl 2-Imino-2-Oxo-2Lambda6-Thia-6-Azaspiro[3.3]Heptane-6-Carboxylate is a high-purity, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is valued for its role as a key building block in the synthesis of novel, complex active pharmaceutical ingredients (APIs). It is primarily sought after by research and development teams and process chemists in the pharmaceutical and biotechnology sectors working on next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the synthesis of complex drug candidates, particularly those targeting neurological and metabolic disorders.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker or component in the design of bifunctional PROTAC molecules for targeted protein degradation.
• Medicinal Chemistry Research: Used in lead optimization and structure-activity relationship (SAR) studies to explore new chemical space and improve drug-like properties.
• Chemical Biology Probes: Employed in the development of tool compounds and probes for studying enzyme function and biological pathways.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and cGMP manufacturing of clinical trial materials.

Basic Information

Product Name	tert-Butyl 2-Imino-2-Oxo-2Lambda6-Thia-6-Azaspiro[3.3]Heptane-6-Carboxylate
CAS No.	2225816-09-9
Molecular Formula	C10H15N3O3S
Molecular Weight	257.31 g/mol
Synonyms	6-(tert-Butoxycarbonyl)-2-imino-2-oxo-2λ⁶-thia-6-azaspiro[3.3]heptane; tert-Butyl 2-imino-2-oxo-2λ⁶-thia-6-azaspiro[3.3]heptane-6-carboxylate; 2-Imino-2-oxo-2λ⁶-thia-6-azaspiro[3.3]heptane-6-carboxylic acid tert-butyl ester; BOC-protected 2-iminothiaspiro[3.3]heptane; 2225816-09-9; 6-Boc-2-imino-2-oxo-2λ⁶-thia-6-azaspiro[3.3]heptane
EINECS	Contact for details

Quality Control

Our tert-Butyl 2-Imino-2-Oxo-2Lambda6-Thia-6-Azaspiro[3.3]Heptane-6-Carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with detailed specifications are provided for every shipment, supporting your regulatory and quality assurance requirements.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This compound may be hygroscopic (moisture-sensitive); handle and store under inert atmosphere (e.g., nitrogen or argon) for long-term stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC/MS)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.