Description

6-Bromo-5-Chloropyridine-3-Boronic Acid is a high-value boronic acid derivative and a versatile building block in modern synthetic chemistry. Its core value proposition lies in enabling the precise construction of complex heterocyclic systems through cross-coupling reactions. This compound is essential for researchers and manufacturers in the pharmaceutical, agrochemical, and advanced materials sectors who require reliable, high-purity intermediates for drug discovery and development.

Application

• Pharmaceutical Intermediate: A key precursor in the synthesis of active pharmaceutical ingredients (APIs), particularly for kinase inhibitors and other small-molecule therapeutics.
• Suzuki-Miyaura Cross-Coupling: Serves as a critical boron-containing partner for constructing biaryl and heterobiaryl structures central to many drug candidates.
• Agrochemical Research: Used in developing novel herbicides, fungicides, and insecticides with specific activity profiles.
• Ligand Synthesis: Employed in the creation of specialized ligands for catalysis and material science applications.
• Chemical Biology Probes: Facilitates the development of molecular probes for target identification and validation in biological systems.
• Material Science: A building block for organic electronic materials, such as those used in OLEDs and organic photovoltaics.

Basic Information

Product Name	6-Bromo-5-Chloropyridine-3-Boronic Acid
CAS No.	2225155-07-5
Molecular Formula	C5H4BBrClNO2
Molecular Weight	236.26 g/mol
Synonyms	(6-Bromo-5-chloropyridin-3-yl)boronic acid; 5-Chloro-6-bromopyridine-3-boronic acid; 3-Borono-6-bromo-5-chloropyridine; 6-Bromo-5-chloro-3-pyridineboronic acid; Boronic acid, B-(6-bromo-5-chloro-3-pyridinyl)-; 2225155-07-5; 6-Br-5-Cl-Py-3-BA
EINECS	Contact for details

Quality Control

Our 6-Bromo-5-Chloropyridine-3-Boronic Acid is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, NMR, and elemental analysis, to ensure high purity and batch-to-batch consistency suitable for research and scale-up. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.