Description

Cyclic Di-Gmp (Sodium Salt) is a high-purity, biologically active nucleotide derivative widely used as a key second messenger in research. This compound, CAS NO 2222132-40-1, is essential for studying bacterial biofilm formation, virulence, and persistence mechanisms. It is a critical reagent for pharmaceutical R&D, microbiology, and molecular biology laboratories focused on developing novel anti-infective strategies.

Application

• Bacterial Signal Transduction Research: Fundamental studies on c-di-GMP signaling pathways regulating motility, virulence, and biofilm formation.
• Pharmaceutical Development: Screening and validation of novel antibacterial targets, such as phosphodiesterases and riboswitches that interact with c-di-GMP.
• Microbiology & Biofilm Studies: Induction and quantitative analysis of bacterial biofilm development in various model systems.
• Enzymology Assays: Substrate for studying the activity of diguanylate cyclases (DGCs) and phosphodiesterases (PDEs).
• Immunology Research: Investigation of the mammalian innate immune response, specifically the STING pathway activation.
• Biochemical Reagent: Used in the preparation of standards, controls, and buffers for analytical and diagnostic applications.

Basic Information

Product Name	Cyclic Di-Gmp (Sodium Salt)
CAS No.	2222132-40-1
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Cyclic diguanylate sodium salt; c-di-GMP sodium salt; Bis(3',5')-cyclic diguanylic acid sodium salt; Cyclic diguanylic acid sodium salt; Cyclic di-GMP; c-di-GMP; 3',5'-Cyclic diguanylic acid sodium; Cyclic diguanosine monophosphate sodium salt
EINECS	Contact for details

Quality Control

Our Cyclic Di-Gmp (Sodium Salt) is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and identity confirmation via spectroscopic methods, to ensure it meets the stringent requirements of research applications. A detailed Certificate of Analysis (COA) is provided with every shipment, guaranteeing traceability, consistency, and reliability for your critical experiments.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below in a dry environment. The product is hygroscopic (moisture-sensitive); allow the vial to equilibrate to room temperature before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	White to off-white powder
Identification (HPLC/UV)	Conforms
Purity (HPLC)	≥95%
Water Content (KF)	≤5.0%
Endotoxin	<10 EU/mg
Solubility	Soluble in water, slightly soluble in DMSO

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.