Description

(3-Iodophenyl)Acetic Acid tert-Butyl Ester is a high-purity, functionalized aromatic ester building block of significant interest in advanced organic synthesis. Its core value lies in the strategic combination of a protected carboxylic acid group and an iodine substituent, which serves as a versatile handle for further cross-coupling reactions. This compound is essential for researchers and process chemists in the pharmaceutical and agrochemical industries, where it is used to construct complex molecular architectures for active ingredient development.

Application

• Pharmaceutical Intermediate: A key synthon in the synthesis of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and inflammatory diseases.
• Agrochemical Research: Used in the development of new herbicides and fungicides, where the iodine atom allows for efficient derivatization to optimize biological activity.
• Ligand and Catalyst Synthesis: Serves as a precursor for creating specialized ligands used in transition metal catalysis, such as palladium-catalyzed cross-couplings.
• Material Science Building Block: Employed in the research and development of advanced organic materials, including liquid crystals and organic semiconductors.
• Peptide Mimetics: The tert-butyl ester group provides a useful protecting strategy in the synthesis of non-natural amino acids and peptide analogs.
• Chemical Biology Probes: Utilized as a starting material for synthesizing tagged molecules used in proteomics and cellular imaging studies.

Basic Information

Product Name	(3-Iodophenyl)Acetic Acid tert-Butyl Ester
CAS No.	2206970-15-0
Molecular Formula	C12H15IO2
Molecular Weight	318.15 g/mol
Synonyms	tert-Butyl (3-iodophenyl)acetate; 2-(3-Iodophenyl)acetic acid 1,1-dimethylethyl ester; 3-Iodobenzeneacetic acid tert-butyl ester; (3-Iodobenzyl)acetic acid tert-butyl ester; tert-Butyl 2-(3-iodophenyl)acetate; Acetic acid, (3-iodophenyl)-, 1,1-dimethylethyl ester; 2206970-15-0
EINECS	Contact for details

Quality Control

Our (3-Iodophenyl)Acetic Acid tert-Butyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure high chemical purity and consistency, meeting the exacting standards required for research and process chemistry. A comprehensive Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep the container tightly sealed to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.