Description

n-Methyl-N'-[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]Urea is a high-purity, advanced pharmaceutical intermediate featuring a unique pyridine-urea scaffold with a trifluoromethyl group. This compound is valued for its role in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in the agrochemical and pharmaceutical research sectors where its structural motifs are leveraged for bioactivity. It is primarily sought by R&D chemists and process development scientists working on innovative crop protection agents and small-molecule drug discovery programs.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, especially those targeting enzyme inhibition.
• Agrochemical Synthesis: Used in the production pathway for advanced herbicides and pesticides, where the trifluoromethylpyridine moiety enhances efficacy and environmental stability.
• Chemical Research: Serves as a versatile scaffold in medicinal chemistry for structure-activity relationship (SAR) studies and lead optimization.
• Custom Synthesis: Employed by contract research and manufacturing organizations (CROs/CMOs) for the custom synthesis of complex molecules for client projects.
• Material Science Research: Investigated as a precursor for specialty chemicals and functional materials due to its unique electronic properties imparted by the fluorine atoms.

Basic Information

Product Name	n-Methyl-N'-[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]Urea
CAS No.	2197056-43-0
Molecular Formula	C9H10F3N3O
Molecular Weight	233.19 g/mol
Synonyms	1-Methyl-3-[2-methyl-6-(trifluoromethyl)pyridin-3-yl]urea; N-Methyl-N'-(2-methyl-6-(trifluoromethyl)pyridin-3-yl)urea; Urea, N-methyl-N'-[2-methyl-6-(trifluoromethyl)-3-pyridinyl]-; 2197056-43-0; 3-Pyridinecarboxamide, N-methyl-6-(trifluoromethyl)-; Methyl-[2-methyl-6-(trifluoromethyl)pyridin-3-yl]urea
EINECS	Contact for details

Quality Control

Our n-Methyl-N'-[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]Urea is manufactured under a strict quality management system. Every batch undergoes comprehensive analytical testing, including HPLC, NMR, and MS, to ensure identity, purity, and consistency. Certificates of Analysis (COA) documenting all critical parameters are provided and available upon request to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, well-ventilated place at controlled room temperature (15-25°C). Keep away from strong acids, strong bases, and oxidizing agents. For long-term storage, consider an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Conforms to reference
Purity (HPLC)	≥ 98.0%
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.