Description

n-Cyclopropyl-N'-[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]Urea is a high-purity, advanced pharmaceutical intermediate featuring a unique trifluoromethylpyridine and cyclopropyl urea scaffold. This compound is of significant commercial interest for its role in the research and development of novel active pharmaceutical ingredients (APIs), particularly in therapeutic areas requiring targeted molecular interactions. It is primarily sought by pharmaceutical R&D laboratories, agrochemical innovators, and fine chemical manufacturers engaged in synthesizing next-generation small molecule drugs and crop protection agents.

Application

• Pharmaceutical Intermediate: A key building block for the synthesis of novel drug candidates, especially in oncology, CNS disorders, and anti-infective therapies.
• Agrochemical Research: Serves as a core structure for developing new herbicides, fungicides, and insecticides with enhanced efficacy and selectivity.
• Chemical Biology Probe: Used in academic and industrial research to study enzyme inhibition and protein-ligand interactions due to its specific hydrogen-bonding motifs.
• Material Science Precursor: Potential intermediate for creating specialty polymers or coatings with unique fluorinated properties.
• Contract Research & Development (CRO/CMO): Supplied to service organizations supporting drug discovery and process chemistry for global clients.

Basic Information

Product Name	n-Cyclopropyl-N'-[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]Urea
CAS No.	2197054-41-2
Molecular Formula	C11H11F3N3O
Molecular Weight	258.22 g/mol
Synonyms	N-Cyclopropyl-N'-(2-methyl-6-(trifluoromethyl)pyridin-3-yl)urea; 1-Cyclopropyl-3-[2-methyl-6-(trifluoromethyl)pyridin-3-yl]urea; Urea, N-cyclopropyl-N'-[2-methyl-6-(trifluoromethyl)-3-pyridinyl]-; 3-Pyridinecarboxamide, N-cyclopropyl-2-methyl-6-(trifluoromethyl)-; (2-Methyl-6-(trifluoromethyl)pyridin-3-yl)carbamic acid cyclopropylamide
EINECS	Contact for details

Quality Control

Our n-Cyclopropyl-N'-[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]Urea is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing all specifications is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from strong acids, bases, and oxidizing agents. For long-term storage, consider under an inert atmosphere to ensure stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Related Substances (HPLC)	Any single impurity ≤ 0.5%, Total impurities ≤ 1.5%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.