Description

Sulfo-Cy7 Alkyne CAS NO 2183440-56-2 is a near-infrared (NIR) fluorescent dye functionalized with a reactive alkyne group and water-solubilizing sulfonate moieties. This compound is engineered for high-performance bio-conjugation via copper-catalyzed azide-alkyne cycloaddition (CuAAC) click chemistry, enabling the sensitive labeling and tracking of biomolecules in aqueous environments. It is an essential tool for researchers and developers in biopharmaceuticals, diagnostic assay development, and advanced life science research who require deep-tissue imaging probes with enhanced solubility and minimal aggregation.

Application

• Bio-conjugation and Probe Development: Covalent labeling of azide-modified antibodies, proteins, peptides, and oligonucleotides for fluorescence detection.
• In Vivo and In Vitro Imaging: Used as a NIR fluorescent tag for deep-tissue imaging, cell tracking, and biodistribution studies due to its high tissue penetration and low autofluorescence.
• Diagnostic Assays: Development of fluorescent immunoassays (FLISA), lateral flow tests, and other diagnostic platforms requiring stable, water-soluble NIR labels.
• Chemical Biology & Drug Discovery: Labeling of small molecule probes for target engagement studies and high-throughput screening applications.
• Material Science: Functionalization of azide-coated nanoparticles, polymers, and surfaces for creating fluorescent nanomaterials.
• Flow Cytometry & Microscopy: Staining and detection of specific cellular targets in complex biological samples.

Basic Information

Product Name	Sulfo-Cy7 Alkyne
CAS No.	2183440-56-2
Molecular Formula	C45H49KN2O7S2
Molecular Weight	833.11 g/mol
Synonyms	Sulfo-Cyanine7 Alkyne; Sulfo Cy7 Alkyne; Cy7 Sulfo Alkyne; 1-(6-((E)-2-((E)-7-(Prop-2-yn-1-yl)-3,3-dimethyl-5-sulfo-1-(5-sulfonatopentyl)indolin-2-ylidene)ethylidene)-2-((E)-1-(5-carboxypentyl)-3,3-dimethyl-5-sulfoindolin-2-ylidene)cyclopent-1-en-1-yl)-7-(prop-2-yn-1-yl)-3,3-dimethyl-5-sulfo-1-(5-sulfonatopentyl)indol-1-ium, Potassium Salt; Potassium 1-(5-carboxypentyl)-2-((1E,3E)-3-(1-(5-carboxypentyl)-3,3-dimethyl-5-sulfo-1,3-dihydro-2H-indol-2-ylidene)prop-1-en-1-yl)-3,3-dimethyl-5-sulfo-3H-indol-1-ium-2-yl)prop-2-yn-1-yl)-3,3-dimethyl-5-sulfo-1-(5-sulfonatopentyl)indol-1-ium
EINECS	Contact for details

Quality Control

Our Sulfo-Cy7 Alkyne is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, mass spectrometry for identity confirmation, and spectrophotometry for optical property validation. We provide a detailed Certificate of Analysis (COA) with every shipment, ensuring traceability and compliance with your research and development requirements. For specific purity grades or custom specifications, please contact our technical team.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive). Allow the vial to equilibrate to room temperature in a dry environment before opening to minimize moisture uptake.

Specification

Item	Specification
Appearance	Dark green to blue-green solid
Identification (HPLC-MS)	Conforms to structure
Purity (HPLC)	≥95.0%
Absorption (λmax)	747 nm ± 5 nm
Emission (λmax)	774 nm ± 5 nm
Extinction Coefficient (ε)	≥ 200,000 cm⁻¹M⁻¹
Water Content (KF)	≤ 5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.