Description

Cy3 Azide CAS NO 2183440-48-2 is a functionalized cyanine dye derivative designed for bioorthogonal click chemistry applications. This compound is critical for researchers and developers requiring high-specificity labeling and conjugation of biomolecules, such as proteins, antibodies, and oligonucleotides. It is primarily utilized in the life sciences, pharmaceutical R&D, and diagnostic reagent manufacturing sectors for advanced imaging, flow cytometry, and assay development.

Application

• Bioorthogonal Labeling: Conjugation to alkyne-modified biomolecules via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC/SPAAC) for fluorescence tagging.
• Live-Cell Imaging: Visualization of cellular processes and tracking of biomolecules in real-time due to its bright near-infrared fluorescence.
• Flow Cytometry: Staining and detection of specific cell surface markers or intracellular targets when conjugated to targeting ligands.
• Protein & Antibody Conjugation: Site-specific labeling of engineered proteins or antibodies for the development of diagnostic kits and therapeutic agents.
• Nucleic Acid Labeling: Tagging of modified oligonucleotides for fluorescence in situ hybridization (FISH) and other genomic applications.
• Material Science: Surface functionalization of nanoparticles and polymers for creating fluorescent probes and sensors.

Basic Information

Product Name	Cy3 Azide
CAS No.	2183440-48-2
Molecular Formula	C37H45N6O3S2+
Molecular Weight	693.92 g/mol
Synonyms	CY3 azide; Sulfo-Cyanine3 azide; Cyanine3 azide; 2-((1E,3E)-5-((E)-1-(6-azidohexyl)-3,3-dimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-1-ethyl-3,3-dimethyl-3H-indol-1-ium; 1-Ethyl-2-((1E,3E)-5-((E)-1-(6-azidohexyl)-3,3-dimethylindolin-2-ylidene)penta-1,3-dien-1-yl)-3,3-dimethyl-3H-indol-1-ium; Azido-Cy3; Azide-functionalized Cy3 dye
EINECS	Contact for details

Quality Control

Our Cy3 Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and performance characteristics is provided with every shipment to ensure compliance with research and development standards.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to prevent condensation and hydrolysis.

Specification

Item	Specification
Appearance	Dark green to blue solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95.0%
Extinction Coefficient	≥ 150,000 cm-1M-1 (at λmax)
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.