Description

Disulfo-Cy5 Amine is a water-soluble, near-infrared (NIR) fluorescent dye derivative functionalized with a primary amine group and two sulfonate moieties for enhanced solubility and stability. This compound is critical for creating bright, stable, and site-specific fluorescent conjugates with minimal aggregation in aqueous biological systems. It is primarily needed by researchers and manufacturers in the biotechnology, pharmaceutical, and diagnostics sectors for advanced labeling applications.

Application

• Bioconjugation & Probe Synthesis: Site-specific labeling of antibodies, proteins, peptides, and oligonucleotides via amine-reactive chemistry (e.g., NHS ester formation).
• Bioimaging & Microscopy: A key component for preparing NIR fluorescent probes for in vitro and in vivo imaging, flow cytometry, and high-content screening.
• Diagnostic Assay Development: Used in the manufacture of fluorescent lateral flow assays, ELISA kits, and other immunoassay detection systems.
• Drug Delivery & Targeting: Conjugation to nanoparticles, liposomes, or drug molecules to track distribution, targeting, and pharmacokinetics.
• Material Science: Functionalization of polymers, hydrogels, and surfaces for sensor development and biomaterial research.

Basic Information

Product Name	Disulfo-Cy5 Amine
CAS No.	2183440-44-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	Disulfo-Cyanine5 amine; Sulfo-Cy5 amine, disulfonated; Cy5 amine, disulfo; 2-((1E,3E)-5-((E)-2-((E)-3-(5-((2-aminoethyl)amino)-1,3-dioxo-1,3-dihydro-2H-benzo[de]isoquinolin-2-yl)allylidene)-4-sulfonatocyclopent-2-en-1-ylidene)ethylidene)-1,3,3-trimethyl-3H-indol-1-ium-5-sulfonate; NIR dye amine; Water-soluble Cy5 amine
EINECS	Contact for details

Quality Control

Our Disulfo-Cy5 Amine is produced under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation, to ensure it meets the high standards required for sensitive life science applications. A comprehensive Certificate of Analysis (COA) detailing purity, absorbance/fluorescence properties, and functional performance is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store desiccated at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the vial to equilibrate to room temperature before opening to minimize moisture condensation.

Specification

Item	Specification
Appearance	Dark blue to green solid
Identification (HPLC/UV-Vis)	Conforms
Purity (HPLC)	≥ 95%
Absorption Maximum (λmax)	~646 - 652 nm
Emission Maximum (λem)	~662 - 668 nm
Extinction Coefficient (ε)	Contact for details
Solubility	Freely soluble in water, DMSO, PBS
Functional Performance	Conjugation efficiency confirmed

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.