Description

(S)-Dtb-Spirosap CAS NO 2177266-21-4 is a high-purity, advanced pharmaceutical intermediate characterized by its specific stereochemistry and spirocyclic structure. This compound is critical for the synthesis of novel active pharmaceutical ingredients (APIs) targeting complex disease pathways. It is primarily required by research institutions and pharmaceutical companies engaged in the development of next-generation therapeutics, particularly in oncology and neurology.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of novel small-molecule drug candidates.
• Proteolysis Targeting Chimera (PROTAC) Development: Used as a specialized linker or component in the design of bifunctional degraders.
• Medicinal Chemistry Research: Serves as a crucial scaffold for structure-activity relationship (SAR) studies and lead optimization.
• Preclinical Drug Development: Employed in the production of compounds for pharmacological and toxicological evaluation.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and scale-up services.
• Academic Research: Utilized in university and institutional labs for exploring new chemical biology mechanisms.

Basic Information

Product Name	(S)-Dtb-Spirosap
CAS No.	2177266-21-4
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	(S)-Dtb-Spirosap; Dtb-Spirosap; Spirosap Intermediate; (S)-enantiomer of Dtb-Spirosap; PROTAC Linker Intermediate; Spirocyclic Pharmaceutical Intermediate; CAS 2177266-21-4
EINECS	Contact for details

Quality Control

Our (S)-Dtb-Spirosap is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC for purity and chiral purity verification, to ensure it meets the exacting standards required for pharmaceutical R&D. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with each shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). This product is hygroscopic (moisture-sensitive) and must be kept under inert atmosphere or in a desiccator after opening to maintain stability and purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Chiral Purity (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.