Description

tert-Butyl 1-Benzyl-3-Iodo-1,8-Diazaspiro[4.5]Decane-8-Carboxylate (Wx102162) is a high-value, complex spirocyclic building block featuring a reactive iodine substituent. This compound matters as a versatile synthetic intermediate, enabling the construction of sophisticated nitrogen-containing heterocycles through cross-coupling and functional group transformations. Pharmaceutical and agrochemical research organizations need it for the discovery and development of novel active ingredients, particularly in medicinal chemistry programs targeting central nervous system (CNS) disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: Key building block in the synthesis of potential drug candidates, especially for neurological targets.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and library synthesis for lead optimization.
• Agrochemical Development: Intermediate in the research and synthesis of novel pesticides and herbicides.
• Chemical Biology Probes: Serves as a precursor for labeled compounds or probes used in biochemical assays.
• Cross-Coupling Reactions: The iodine atom facilitates advanced synthetic routes like Suzuki, Sonogashira, or Buchwald-Hartwig amination reactions.
• Spirocyclic Scaffold Synthesis: Core structure for developing new chemical entities with unique three-dimensional properties.

Basic Information

Product Name	tert-Butyl 1-Benzyl-3-Iodo-1,8-Diazaspiro[4.5]Decane-8-Carboxylate (Wx102162)
CAS No.	2177264-11-6
Molecular Formula	C20H29IN2O2
Molecular Weight	456.37 g/mol
Synonyms	1,8-Diazaspiro[4.5]decane-8-carboxylic acid, 1-(phenylmethyl)-3-iodo-, 1,1-dimethylethyl ester; tert-Butyl 1-benzyl-3-iodo-1,8-diazaspiro[4.5]decane-8-carboxylate; WX-102162; Wx102162; 1-Benzyl-3-iodo-1,8-diazaspiro[4.5]decane-8-carboxylic acid tert-butyl ester; 3-Iodo-1-benzyl-1,8-diazaspiro[4.5]decane-8-carboxylic acid tert-butyl ester
EINECS	Contact for details

Quality Control

Our tert-Butyl 1-Benzyl-3-Iodo-1,8-Diazaspiro[4.5]Decane-8-Carboxylate is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity for research applications. Each lot undergoes comprehensive analytical characterization, including HPLC, NMR, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and impurity profiles is provided with every shipment to support your regulatory and R&D documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). The compound is light-sensitive; prolonged exposure to light should be avoided. Keep the container tightly sealed in a dry environment to minimize moisture uptake.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.