Description

tert-Butyl 6-(2-Ethoxy-2-Oxoethyl)-2-azaspiro[3.3]heptane-2-carboxylate is a sophisticated, high-purity organic building block featuring a unique spirocyclic and ester-functionalized structure. This compound is of significant value in pharmaceutical research and development, serving as a critical intermediate for the synthesis of novel active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, agrochemical, and advanced material sectors who require reliable, high-quality intermediates for complex synthetic routes.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex drug candidates, particularly those targeting central nervous system (CNS) disorders.
• Agrochemical Synthesis: Used in the research and development of novel pesticides and herbicides, leveraging its spirocyclic scaffold.
• Chemical Biology Probe Development: Serves as a precursor for creating molecular probes to study enzyme function and biological pathways.
• Material Science Research: Employed in the development of specialty polymers and advanced organic materials with tailored properties.
• Process Chemistry & Scale-Up: Provides a reliable intermediate for optimizing synthetic routes from laboratory to pilot and commercial scale.
• Custom Synthesis & Contract Manufacturing: A critical starting material for fine chemical manufacturers offering bespoke synthesis services.

Basic Information

Product Name	tert-Butyl 6-(2-Ethoxy-2-Oxoethyl)-2-azaspiro[3.3]heptane-2-carboxylate
CAS No.	2173992-27-1
Molecular Formula	C16H27NO4
Molecular Weight	297.39 g/mol
Synonyms	2-Azaspiro[3.3]heptane-2-carboxylic acid, 6-(2-ethoxy-2-oxoethyl)-, 1,1-dimethylethyl ester; 6-(2-Ethoxy-2-oxoethyl)-2-azaspiro[3.3]heptane-2-carboxylic acid tert-butyl ester; tert-Butyl 6-(2-ethoxy-2-oxoethyl)-2-azaspiro[3.3]heptane-2-carboxylate; 2173992-27-1; BOC-protected azaspiroheptane ethyl acetate; tert-Butyl 6-(carbethoxymethyl)-2-azaspiro[3.3]heptane-2-carboxylate
EINECS	Contact for details

Quality Control

Our tert-Butyl 6-(2-Ethoxy-2-Oxoethyl)-2-azaspiro[3.3]heptane-2-carboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with every shipment, detailing all critical quality attributes. Our production adheres to cGMP principles where required, ensuring reliability for research and scale-up applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider holding under an inert atmosphere to maintain optimal purity.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Any single unknown impurity	≤ 0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.