Description

(1S,2R)-Ethyl 2-(tert-Butoxycarbonyl)Cyclohexanecarboxylate is a high-purity, stereochemically defined chiral building block essential for advanced organic synthesis. This compound is valued for its role as a key intermediate in the production of complex pharmaceutical molecules and fine chemicals, where precise stereochemistry is critical for biological activity. It is primarily needed by research institutions and manufacturers in the pharmaceutical, agrochemical, and specialty chemical industries for developing new active ingredients and novel materials.

Application

• Pharmaceutical Intermediate: A critical chiral synthon for the synthesis of active pharmaceutical ingredients (APIs), particularly in the development of central nervous system (CNS) drugs and antiviral agents.
• Agrochemical Synthesis: Used in the research and production of advanced, stereoselective pesticides and herbicides.
• Asymmetric Catalysis: Serves as a precursor or ligand in the development of chiral catalysts for enantioselective reactions.
• Fine Chemical Production: Employed in the manufacture of complex fragrances, flavors, and other high-value specialty chemicals requiring specific stereochemistry.
• Academic & Industrial R&D: A valuable tool for medicinal chemistry research and process development in organic synthesis laboratories.
• Peptidomimetics & Prodrug Development: Used in constructing conformationally constrained peptide analogs and designing prodrugs with improved bioavailability.

Basic Information

Product Name	(1S,2R)-Ethyl 2-(tert-Butoxycarbonyl)Cyclohexanecarboxylate
CAS No.	2173637-09-5
Molecular Formula	C15H26O4
Molecular Weight	270.36 g/mol
Synonyms	Ethyl (1S,2R)-2-[(tert-Butoxy)carbonyl]cyclohexane-1-carboxylate; (1S,2R)-2-(Boc)Cyclohexanecarboxylic Acid Ethyl Ester; trans-Ethyl 2-(tert-Butoxycarbonyl)cyclohexanecarboxylate; Boc-Protected Cyclohexanecarboxylic Acid Ethyl Ester; (1S,2R)-1-Ethoxycarbonyl-2-(tert-butoxycarbonyl)cyclohexane; Ethyl trans-2-(Boc-amino)cyclohexanecarboxylate (common misnomer); Chiral Ethyl 2-Boc-cyclohexanecarboxylate
EINECS	Contact for details

Quality Control

Our (1S,2R)-Ethyl 2-(tert-Butoxycarbonyl)Cyclohexanecarboxylate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral HPLC and NMR, to ensure high enantiomeric excess (ee) and chemical purity meeting the stringent requirements for pharmaceutical intermediates. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee traceability, consistency, and compliance with your R&D and production specifications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated area at a controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid or low-melting solid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Enantiomeric Excess (Chiral HPLC)	≥ 99.0% ee
Water Content (KF)	≤ 0.5%
Residual Solvents (GC)	Meets ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.