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Imidazo[1,2-A]Pyridine, 6-Bromo-8-Iodo-3-Methyl- CAS NO 2172078-81-6
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CAS No.:2172078-81-6
Grade:Pharmacy Grade
Content:99.9%
Brand:Customizable
Packaging:Customizable
Description
Imidazo[1,2-A]Pyridine, 6-Bromo-8-Iodo-3-Methyl- is a high-value, multi-halogenated heterocyclic building block essential for advanced organic synthesis. Its core value lies in enabling the precise construction of complex molecular architectures, particularly in the development of novel pharmaceuticals and agrochemicals. This compound is critically needed by research chemists and process development scientists in the pharmaceutical, agrochemical, and material science industries for creating targeted bioactive molecules.
Application
- Pharmaceutical Intermediate: Key precursor in the synthesis of potential drug candidates, especially for kinase inhibitors and other targeted therapies.
- Agrochemical Research: Building block for developing new active ingredients with herbicidal, fungicidal, or insecticidal properties.
- Material Science: Used in the research and development of organic electronic materials, such as OLEDs and semiconductors.
- Chemical Biology: Serves as a versatile scaffold for creating molecular probes and tool compounds for biological target validation.
- Cross-Coupling Reactions: The bromo and iodo substituents make it an excellent substrate for Suzuki, Sonogashira, and Buchwald-Hartwig cross-coupling reactions.
- Library Synthesis: Enables the rapid generation of diverse compound libraries for high-throughput screening in drug discovery programs.
Basic Information
| Item | Details |
|---|---|
| Product Name | Imidazo[1,2-A]Pyridine, 6-Bromo-8-Iodo-3-Methyl- |
| CAS No. | 2172078-81-6 |
| Molecular Formula | C8H6BrIN2 |
| Molecular Weight | 352.96 g/mol |
| Synonyms | 6-Bromo-8-iodo-3-methylimidazo[1,2-a]pyridine; 3-Methyl-6-bromo-8-iodoimidazo[1,2-a]pyridine; 6-Bromo-8-iodo-3-methyl-[1,2,4]triazolo[4,3-a]pyridine (common misnomer); Imidazo[1,2-a]pyridine, 6-bromo-8-iodo-3-methyl-; 2172078-81-6; Bromo-iodo-methylimidazopyridine; Halogenated imidazopyridine building block |
| EINECS | Contact for details |
Quality Control
Our Imidazo[1,2-A]Pyridine, 6-Bromo-8-Iodo-3-Methyl- is manufactured under strict quality control protocols to ensure batch-to-batch consistency and high purity, typically ≥95% (HPLC). Each lot is accompanied by a comprehensive Certificate of Analysis (COA) detailing purity, identity confirmation via spectroscopic methods (NMR, IR, MS), and levels of any residual solvents or impurities. We adhere to cGMP principles where applicable to support our clients' regulatory and research needs.
Storage
Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This compound is light-sensitive and should be handled under inert atmosphere when appropriate for prolonged use to ensure long-term stability.
Specification
| Item | Specification |
|---|---|
| Appearance | Off-white to light yellow crystalline powder |
| Identification (IR) | Conforms to structure |
| Identification (NMR) | Conforms to structure |
| Purity (HPLC) | ≥ 95.0% |
| Melting Point | Contact for details |
| Heavy Metals | < 20 ppm |
| Residual Solvents (GC) | Meets ICH guidelines |
Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.
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