Description

Nh-Bis(C1-Peg1-Boc) is a specialized bifunctional PEG-based Boc-protected amine reagent, identified by CAS No. 2171072-53-8. This compound is engineered to serve as a critical building block in the synthesis of complex molecules, offering controlled reactivity and enhanced solubility. It is primarily utilized by researchers and process chemists in the pharmaceutical and bioconjugation sectors for developing novel therapeutics, drug delivery systems, and advanced materials.

Application

• Pharmaceutical Intermediate: A key synthon in the development of active pharmaceutical ingredients (APIs) and prodrugs.
• Bioconjugation & Linker Chemistry: Used to create stable, cleavable linkers for antibody-drug conjugates (ADCs) and protein-polymer conjugates.
• Polymer & Material Science: Serves as a functional monomer or cross-linking agent for synthesizing smart polymers and hydrogels.
• Peptide Synthesis: Facilitates the introduction of PEG spacers and protected amine groups during solid-phase and solution-phase peptide synthesis.
• Proteomics Research: Employed as a reagent for labeling and modifying biomolecules to study protein interactions and functions.
• Chemical Biology Tool: Useful for probing biological systems and developing chemical probes due to its orthogonal protecting group and PEG moiety.

Basic Information

Product Name	Nh-Bis(C1-Peg1-Boc)
CAS No.	2171072-53-8
Molecular Formula	Contact for details
Molecular Weight	Contact for details
Synonyms	1,8-Bis(Boc-amino)-3,6-dioxaoctane; 2,2'-(Ethane-1,2-diylbis(oxy))bis(ethan-1-amine) N,N'-di-tert-butyl dicarbonate derivative; NH2-PEG2-NHBoc; Boc-NH-PEG2-NH-Boc; Diamino-PEG2-di-Boc; 1,8-Diamino-3,6-dioxaoctane di-Boc derivative; Bis-Boc-protected PEG2 diamine
EINECS	Contact for details

Quality Control

Our products undergo rigorous quality testing to ensure compliance with industry standards for research and development. Each batch is characterized using advanced analytical techniques to confirm identity, purity, and consistency. Certificates of Analysis (COA) detailing specific results for parameters such as assay, impurity profile, and moisture content are available upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent moisture absorption and degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Assay (HPLC)	≥95.0%
Water Content (KF)	≤1.0%
Related Substances (HPLC)	Total impurities ≤5.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.