Description

2'-(Methylsulfonyl)-7',8'-Dihydro-6'H-Spiro[Cyclohexane-1,9'-Pyrazino[1',2':1,5]Pyrrolo[2,3-D]Pyrimidin]-6'-One is a sophisticated spirocyclic heterocyclic compound that serves as a critical building block in modern pharmaceutical research and development. Its complex molecular architecture, featuring fused pyrazino-pyrrolo-pyrimidine and cyclohexane rings, makes it a valuable intermediate for constructing novel drug candidates targeting complex diseases. This high-purity compound is primarily utilized by research institutions and pharmaceutical companies engaged in medicinal chemistry and process development.

Application

• Pharmaceutical Intermediate: Key synthetic precursor in the development of novel small-molecule therapeutics.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and library synthesis.
• Kinase Inhibitor Development: Potential intermediate in the synthesis of compounds targeting protein kinases due to its privileged heterocyclic structure.
• Oncology Drug Discovery: Employed in research programs aimed at discovering new anti-cancer agents.
• Process Chemistry & Scale-Up: Serves as a reference standard or starting material for optimizing synthetic routes from lab to pilot scale.
• Contract Research & Manufacturing (CRO/CMO): Supplied to organizations providing custom synthesis and development services.
• Academic Research: Used in universities and institutes for fundamental studies in organic synthesis and heterocyclic chemistry.

Basic Information

Product Name	2'-(Methylsulfonyl)-7',8'-Dihydro-6'H-Spiro[Cyclohexane-1,9'-Pyrazino[1',2':1,5]Pyrrolo[2,3-D]Pyrimidin]-6'-One
CAS No.	2170747-01-8
Molecular Formula	C18H22N4O3S
Molecular Weight	374.46 g/mol
Synonyms	7',8'-Dihydro-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one, 2'-(methylsulfonyl)-; 2'-(Methylsulfonyl)-7',8'-dihydrospiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'(1'H)-one; Spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one, 2'-(methylsulfonyl)-7',8'-dihydro-; CAS 2170747-01-8
EINECS	Contact for details

Quality Control

Our 2'-(Methylsulfonyl)-7',8'-Dihydro-6'H-Spiro[Cyclohexane-1,9'-Pyrazino[1',2':1,5]Pyrrolo[2,3-D]Pyrimidin]-6'-One is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and residual solvent analysis to ensure it meets the exacting standards required for pharmaceutical R&D. A detailed Certificate of Analysis (COA) is provided with every shipment, documenting all critical quality attributes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (typically 15-25°C). For long-term storage, consider storing under an inert atmosphere to ensure optimal stability. Keep the container tightly sealed in a dry environment to protect this compound from moisture.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Retention time corresponds to reference standard
Identification (NMR)	Spectrum consistent with structure
Purity (HPLC)	≥ 95.0% (Area Percent)
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.