Description

2'-(Methylthio)-7',8'-Dihydro-6'H-Spiro[Cyclohexane-1,9'-Pyrazino[1',2':1,5]Pyrrolo[2,3-D]Pyrimidin]-6'-One is a sophisticated spirocyclic heterocyclic compound that serves as a critical building block in advanced pharmaceutical research and development. Its unique molecular architecture, featuring fused pyrazino-pyrrolo-pyrimidine and cyclohexane rings, makes it a valuable scaffold for modulating biological activity and exploring novel therapeutic pathways. This high-purity intermediate is primarily utilized by medicinal chemists and R&D teams in the pharmaceutical and biotechnology sectors for the synthesis of targeted drug candidates.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel small-molecule therapeutics.
• Medicinal Chemistry Research: Used as a core scaffold or building block for structure-activity relationship (SAR) studies and lead optimization.
• Kinase Inhibitor Development: Potential application in the synthesis of compounds targeting specific kinase enzymes involved in various disease pathways.
• Chemical Biology Probes: Serves as a starting material for creating specialized probes to study biological processes and protein functions.
• Contract Research & Development (CRO): Supplied to CROs and academic institutions engaged in cutting-edge drug discovery programs.
• Process Chemistry: Used in route scouting and scale-up studies for the production of active pharmaceutical ingredients (APIs).

Basic Information

Product Name	2'-(Methylthio)-7',8'-Dihydro-6'H-Spiro[Cyclohexane-1,9'-Pyrazino[1',2':1,5]Pyrrolo[2,3-D]Pyrimidin]-6'-One
CAS No.	2170747-00-7
Molecular Formula	C16H20N4OS
Molecular Weight	316.42 g/mol
Synonyms	7',8'-Dihydro-2'-(methylthio)-6'H-spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidin]-6'-one; 2-Methylsulfanyl-7,8-dihydro-6H-spiro[cyclohexane-1,9-pyrazino[1,2:1,5]pyrrolo[2,3-d]pyrimidin]-6-one; Spiro[cyclohexane-1,9'-pyrazino[1',2':1,5]pyrrolo[2,3-d]pyrimidine] derivative; CAS 2170747-00-7
EINECS	Contact for details

Quality Control

Every batch of 2'-(Methylthio)-7',8'-Dihydro-6'H-Spiro[Cyclohexane-1,9'-Pyrazino[1',2':1,5]Pyrrolo[2,3-D]Pyrimidin]-6'-One is manufactured and tested under a strict quality management system. We provide comprehensive analytical data to ensure the identity, purity, and consistency required for sensitive research applications. Certificates of Analysis (COA) detailing purity (typically by HPLC), identity confirmation (by NMR, MS, and IR), and impurity profiles are available for each lot and provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at controlled room temperature (15-25°C) in a dry, well-ventilated area. For long-term storage, consider storing under an inert atmosphere to ensure optimal stability.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.