Description

Picolyl-Azide-Nh2 CAS NO 2168629-06-7 is a specialized bifunctional chemical building block featuring both an azide and a primary amine group on a picolyl scaffold. This unique structure makes it a critical reagent for click chemistry and bioconjugation applications, enabling the rapid and selective formation of stable triazole linkages. It is primarily utilized by researchers and manufacturers in the pharmaceutical, agrochemical, and materials science industries for the development of novel compounds, targeted drug delivery systems, and advanced polymeric materials.

Application

• Pharmaceutical Intermediate: Key building block for the synthesis of active pharmaceutical ingredients (APIs) and antibody-drug conjugates (ADCs) via copper-catalyzed azide-alkyne cycloaddition (CuAAC).
• Bioconjugation & Probe Development: Used for labeling biomolecules (proteins, peptides, oligonucleotides) with fluorescent dyes, affinity tags, or other functional moieties.
• Polymer & Materials Science: Serves as a functional monomer or cross-linker for creating smart polymers, hydrogels, and surface-modified materials with tailored properties.
• Agrochemical Research: Employed in the design and synthesis of novel crop protection agents and plant growth regulators.
• Chemical Biology Tool: Facilitates activity-based protein profiling (ABPP) and the study of biomolecular interactions in complex systems.
• Diagnostic Reagent Synthesis: Used in the production of components for diagnostic assays and imaging agents.

Basic Information

Product Name	Picolyl-Azide-Nh2
CAS No.	2168629-06-7
Molecular Formula	C7H9N5
Molecular Weight	163.18 g/mol
Synonyms	2-(Azidomethyl)pyridin-3-amine; 3-Amino-2-(azidomethyl)pyridine; 2-(Azidomethyl)-3-pyridinamine; Picolyl Azide Amine; 3-Pyridinamine, 2-(azidomethyl)-; Azido-Picolyl-Amine; Click Chemistry Amine Reagent; Bifunctional Picolyl Linker
EINECS	Contact for details

Quality Control

Our Picolyl-Azide-Nh2 is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity assessment and NMR for structural confirmation, to ensure compliance with high-purity research and production standards. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at 2-8°C under an inert atmosphere (e.g., nitrogen or argon) due to its sensitivity to oxidation and light. Keep away from heat, sparks, open flames, and strong oxidizing agents.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.