Description

Benzenepropanoic Acid, 4-Bromo-α-Hydroxy-, Methyl Ester, (αr)- is a chiral, high-purity organic intermediate of significant interest in advanced chemical synthesis. This compound matters for its role as a critical building block in the development of complex, optically active molecules, particularly within the pharmaceutical sector. It is primarily needed by research institutions and industrial manufacturers engaged in the production of active pharmaceutical ingredients (APIs), agrochemicals, and specialty fine chemicals where precise stereochemistry is essential.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of novel therapeutic agents, including potential central nervous system (CNS) drugs and anti-inflammatory compounds.
• Agrochemical Synthesis: Used in the production of advanced, enantiomerically pure pesticides and herbicides to enhance efficacy and reduce environmental impact.
• Ligand and Catalyst Development: Serves as a precursor for synthesizing chiral ligands and organocatalysts used in asymmetric synthesis.
• Fine Chemical Production: Employed in the manufacture of specialty chemicals, flavors, and fragrances requiring specific stereochemical configurations.
• Academic and R&D Laboratories: A valuable reagent for methodological studies in organic chemistry and stereoselective synthesis.

Basic Information

Product Name	Benzenepropanoic Acid, 4-Bromo-α-Hydroxy-, Methyl Ester, (αr)-
CAS No.	2166118-09-6
Molecular Formula	C10H11BrO3
Molecular Weight	259.10 g/mol
Synonyms	(R)-Methyl 4-Bromo-3-hydroxy-3-phenylpropanoate; (R)-Methyl 3-(4-Bromophenyl)-3-hydroxypropanoate; (R)-4-Bromo-α-Hydroxybenzenepropanoic Acid Methyl Ester; (R)-Methyl 4-Bromo-β-hydroxyhydrocinnamate; (R)-Methyl 3-Hydroxy-3-(4-bromophenyl)propanoate; (αR)-4-Bromo-α-hydroxybenzenepropanoic Acid Methyl Ester; (R)-3-(4-Bromophenyl)-3-hydroxypropionic Acid Methyl Ester
EINECS	Contact for details

Quality Control

Our Benzenepropanoic Acid, 4-Bromo-α-Hydroxy-, Methyl Ester, (αr)- is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including chiral purity analysis by HPLC, to ensure it meets the high standards required for pharmaceutical and fine chemical applications. Certificates of Analysis (COA) detailing identity, purity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). The compound is light-sensitive and should be handled under appropriate conditions to maintain stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Assay (HPLC)	≥ 98.0%
Chiral Purity (HPLC)	≥ 99.0% ee
Loss on Drying	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.