Description

Cyclopropanepropanoic Acid, α-Hydroxy-, Methyl Ester, (αs)- is a specialized chiral building block and synthetic intermediate of significant interest in advanced organic synthesis. This compound, with CAS number 2165755-17-7, is valued for its unique cyclopropane ring structure, which imparts specific steric and electronic properties to target molecules. It is primarily utilized by research chemists and process development scientists in the pharmaceutical and agrochemical industries for the construction of complex, biologically active molecules.

Application

• Pharmaceutical Intermediate: Serves as a key chiral synthon in the research and development of novel active pharmaceutical ingredients (APIs), particularly for candidates targeting central nervous system (CNS) disorders and metabolic diseases.
• Agrochemical Synthesis: Used in the synthesis of advanced pesticides and herbicides, where the cyclopropane moiety can enhance biological activity and environmental stability.
• Ligand and Catalyst Development: Acts as a precursor for chiral ligands and organocatalysts used in asymmetric synthesis to induce high enantioselectivity.
• Material Science Research: Investigated as a monomer or modifying agent for creating polymers with tailored thermal and mechanical properties.
• Academic & Industrial R&D: Employed in methodological studies and scale-up process optimization for complex organic transformations.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing unique aroma compounds with complex, strained-ring backbones.

Basic Information

Product Name	Cyclopropanepropanoic Acid, α-Hydroxy-, Methyl Ester, (αs)-
CAS No.	2165755-17-7
Molecular Formula	C7H12O3
Molecular Weight	144.17 g/mol
Synonyms	(αS)-α-Hydroxycyclopropanepropanoic Acid Methyl Ester; Methyl (S)-2-Hydroxy-2-cyclopropylacetate; (S)-Methyl 2-Cyclopropyl-2-hydroxyacetate; (S)-2-Hydroxy-2-cyclopropylacetic Acid Methyl Ester; (S)-Methyl Oxycyclopropylacetate; (αS)-Cyclopropanepropanoic Acid, α-Hydroxy-, Methyl Ester; (S)-Methyl 2-Hydroxy-2-cyclopropylethanoate
EINECS	Contact for details

Quality Control

Our production of Cyclopropanepropanoic Acid, α-Hydroxy-, Methyl Ester, (αs)- adheres to stringent internal quality standards to ensure batch-to-batch consistency and high chemical purity. Each lot is fully characterized and undergoes rigorous analytical testing, including chiral purity assessment via HPLC. A comprehensive Certificate of Analysis (COA) detailing identity, purity, enantiomeric excess, and impurity profiles is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (typically 15-25°C). Keep away from strong alkalis and incompatible organic solvents. For long-term storage under inert atmosphere, please contact our technical team for specific recommendations.

Specification

Item	Specification
Appearance	Colorless to pale yellow liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Enantiomeric Excess (Chiral HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.