Description

5-Tamra Amine is a high-purity, amine-reactive fluorescent dye derivative, essential for advanced bioconjugation and labeling applications. Its core value lies in providing a bright, orange-red fluorescent signal with excellent photostability, enabling sensitive detection and imaging in complex biological systems. This compound is critically needed by researchers and manufacturers in the life sciences, particularly for developing fluorescent probes, antibodies, and nucleic acid labels for diagnostics and cellular analysis.

Application

• Fluorescent Probe Synthesis: A key precursor for creating active ester derivatives (e.g., NHS ester, SE) used to label proteins, peptides, and antibodies.
• Nucleic Acid Labeling: Used in the preparation of fluorescently tagged oligonucleotides for FISH (Fluorescence In Situ Hybridization), microarrays, and real-time PCR applications.
• Bioconjugation & Biomarker Development: Enables the covalent attachment of fluorescent tags to various biomolecules for flow cytometry, immunohistochemistry (IHC), and Western blotting.
• Diagnostic Assay Manufacturing: Integral to the production of reagents for clinical diagnostics, including lateral flow assays and ELISA kits requiring high-sensitivity fluorescence detection.
• Cell Imaging & Tracking: Serves as a building block for cell-permeable dyes to visualize cellular structures and track dynamic processes in live-cell imaging.
• Material Science & Sensor Development: Employed in the functionalization of nanoparticles and polymers to create smart materials and chemical sensors.

Basic Information

Product Name	5-Tamra Amine
CAS No.	2158336-48-0
Molecular Formula	C27H28N4O6
Molecular Weight	504.54 g/mol
Synonyms	5-Carboxytetramethylrhodamine amine; 5-TAMRA, SE precursor; 6-Isomer of TAMRA amine; 5-Carboxy-N,N,N',N'-tetramethylrhodamine amine; Tetramethylrhodamine-5-carbonyl azide precursor; 5-TAMRA-NH2; TAMRA(5) amine; Rhodamine derivative amine, 5-isomer
EINECS	Contact for details

Quality Control

Our 5-Tamra Amine is manufactured under strict quality systems to ensure batch-to-batch consistency and high performance in sensitive applications. Each lot undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and MS for identity verification. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to support your quality assurance and regulatory documentation needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 2-8°C. The product is hygroscopic (moisture-sensitive); ensure the container is sealed under inert atmosphere or with desiccant after each use to maintain stability and prevent degradation. For long-term storage, consider keeping the material at -20°C under argon or nitrogen.

Specification

Item	Specification
Appearance	Orange to red solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Absorption (λmax)	540 - 550 nm
Emission (λmax)	565 - 580 nm
Water Content (KF)	≤ 2.0%
Heavy Metals	≤ 20 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.