Description

5,8,11,14-Tetraoxa-2-Azaheptadecanedioic Acid, 17-(1,1-Dimethylethyl) 1-(9H-Fluoren-9-Ylmethyl) Ester is a specialized, high-purity chemical building block designed for advanced synthetic applications. This compound is valued for its role as a protected, multifunctional linker molecule, enabling precise chemical modifications in complex synthesis. It is primarily utilized by research institutions and pharmaceutical development teams working on peptide mimetics, bioconjugation, and the synthesis of novel drug candidates and advanced materials.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of complex active pharmaceutical ingredients (APIs) and novel drug candidates.
• Peptide Chemistry & Bioconjugation: Serves as a versatile linker for solid-phase peptide synthesis (SPPS) and for attaching functional groups, fluorophores, or drug molecules to peptides, proteins, or antibodies.
• Protecting Group Strategy: The tert-butyl (Boc) and fluorenylmethyloxycarbonyl (Fmoc) protecting groups allow for orthogonal deprotection, facilitating complex multi-step synthetic sequences.
• Polymer & Material Science: Used in the development of functionalized polymers, dendrimers, and smart materials requiring specific, tunable chemical linkages.
• Research & Development: Essential for academic and industrial R&D in medicinal chemistry, chemical biology, and probe development.
• Diagnostic Reagent Synthesis: Employed in creating specialized reagents and probes for diagnostic assays and imaging applications.

Basic Information

Product Name	5,8,11,14-Tetraoxa-2-Azaheptadecanedioic Acid, 17-(1,1-Dimethylethyl) 1-(9H-Fluoren-9-Ylmethyl) Ester
CAS No.	2148295-94-5
Molecular Formula	C33H45NO8
Molecular Weight	583.72 g/mol
Synonyms	Fmoc-N-amido-PEG4-acid; Fmoc-NH-PEG4-CH2CH2COOH; 17-(tert-Butyl) 1-((((9H-fluoren-9-yl)methoxy)carbonyl)amino)-3,6,9,12-tetraoxapentadecanedioate; Fmoc-8-amino-3,6-dioxaoctanoic acid tert-butyl ester derivative; Boc-NH-PEG4-Fmoc; PEG4-based Fmoc/Boc protected linker; Amino-PEG4-acid Fmoc/Boc protected; Polyethylene glycol derivative linker
EINECS	Contact for details

Quality Control

Our production of 5,8,11,14-Tetraoxa-2-Azaheptadecanedioic Acid, 17-(1,1-Dimethylethyl) 1-(9H-Fluoren-9-Ylmethyl) Ester adheres to stringent quality management protocols to ensure batch-to-batch consistency and high purity, critical for sensitive research and pharmaceutical applications. All products undergo rigorous analytical testing, including HPLC, NMR, and mass spectrometry. Certificates of Analysis (COA) detailing purity, identity, and impurity profiles are provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below for long-term stability. For short-term use, the product may be stored at 2-8°C. Allow the sealed container to reach room temperature before opening to minimize moisture condensation. The material is light-sensitive (store away from light).

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.