Description

8-(Benzo[B]Thiophen-4-Yl)-5,8-Diazaspiro[4.5]Decan-5-Ium Chloride is a high-purity, advanced pharmaceutical intermediate featuring a complex spirocyclic and benzothiophene-based structure. This compound is of significant commercial value for its role as a key building block in the synthesis of novel active pharmaceutical ingredients (APIs), particularly in central nervous system (CNS) and oncology research. It is primarily required by pharmaceutical R&D laboratories, contract research organizations (CROs), and fine chemical manufacturers engaged in developing next-generation therapeutics.

Application

• Pharmaceutical Intermediate: A critical precursor in the multi-step synthesis of novel drug candidates targeting specific receptors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies and lead optimization for new chemical entities.
• CNS Drug Development: Serves as a core scaffold for compounds being investigated for neurological and psychiatric disorders.
• Oncology Research: Employed in the development of targeted small-molecule therapies and kinase inhibitors.
• Chemical Biology: Utilized as a tool compound or probe to study biological pathways and protein interactions.
• Process Chemistry & Scale-Up: Supplied for route scouting, optimization, and pilot-scale production under cGMP conditions.

Basic Information

Product Name	8-(Benzo[B]Thiophen-4-Yl)-5,8-Diazaspiro[4.5]Decan-5-Ium Chloride
CAS No.	2143944-64-1
Molecular Formula	C17H21ClN2S
Molecular Weight	320.88 g/mol
Synonyms	8-(1-Benzothiophen-4-yl)-5,8-diazaspiro[4.5]decan-5-ium chloride; 5,8-Diazaspiro[4.5]decan-5-ium, 8-(1-benzothiophen-4-yl)-, chloride; 8-(Benzo[b]thiophen-4-yl)-5,8-diazaspiro[4.5]decan-5-ium chloride; CAS 2143944-64-1; 8-(1-Benzothiophen-4-yl)-5,8-diazaspiro[4.5]decan-5-ium chloride; 8-(Benzothiophen-4-yl)-5,8-diazaspiro[4.5]decan-5-ium chloride
EINECS	Contact for details

Quality Control

Our 8-(Benzo[B]Thiophen-4-Yl)-5,8-Diazaspiro[4.5]Decan-5-Ium Chloride is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical quality attributes. Our production can be aligned with cGMP guidelines for advanced pharmaceutical applications upon request.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). The container should be kept in a well-ventilated area and protected from moisture. For long-term storage, consider under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms
Identification (NMR)	Conforms
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity	≤ 0.5%
Total Impurities	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.