Description

1-Oxa-2,7-Diazaspiro[4.5]Dec-2-Ene-3-Carboxylic Acid is a sophisticated spirocyclic heterocyclic building block of significant interest in modern synthetic chemistry. This compound serves as a key intermediate for constructing complex molecular architectures, particularly in the development of novel pharmaceuticals. It is primarily sought after by research institutions and pharmaceutical companies engaged in drug discovery programs targeting a range of therapeutic areas.

Application

• Pharmaceutical Intermediate: A critical building block for synthesizing novel active pharmaceutical ingredients (APIs), particularly in medicinal chemistry research.
• Proteolysis-Targeting Chimera (PROTAC) Development: Used in the construction of linker molecules and warhead components for targeted protein degradation therapeutics.
• Kinase Inhibitor Synthesis: Serves as a core scaffold or a functionalized fragment in the design and synthesis of potential kinase inhibitors.
• Chemical Biology Probe Development: Employed to create tool compounds for studying biological pathways and target validation.
• Peptidomimetic Research: Its structure is valuable for designing and synthesizing peptidomimetics to modulate protein-protein interactions.
• Agrochemical Research: Potential intermediate in the discovery of new active ingredients for crop protection.

Basic Information

Product Name	1-Oxa-2,7-Diazaspiro[4.5]Dec-2-Ene-3-Carboxylic Acid
CAS No.	2140326-78-7
Molecular Formula	C8H10N2O3
Molecular Weight	182.18 g/mol
Synonyms	1-Oxa-2,7-diazaspiro[4.5]dec-2-ene-3-carboxylic acid; 2,7-Diazaspiro[4.5]dec-2-ene-3-carboxylic acid, 1-oxa-; 1-Oxa-2,7-diazaspiro[4.5]dec-2-ene-3-carboxylic acid (CAS 2140326-78-7); Spiro[4.5]decane-3-carboxylic acid, 1-oxa-2,7-diaza-2-ene derivative; 3-Carboxy-1-oxa-2,7-diazaspiro[4.5]dec-2-ene; 1-Oxa-2,7-diazaspiro[4.5]dec-2-en-3-oic acid
EINECS	Contact for details

Quality Control

Our 1-Oxa-2,7-Diazaspiro[4.5]Dec-2-Ene-3-Carboxylic Acid is produced under strict quality management protocols. Each batch undergoes rigorous analytical testing, including HPLC, NMR, and MS, to ensure high purity and batch-to-batch consistency suitable for research and development applications. A comprehensive Certificate of Analysis (COA) detailing identity, purity, and impurity profiles is provided with every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). For long-term storage, consider storing under an inert atmosphere at -20°C. The material may be hygroscopic; keep the container tightly sealed in a dry environment.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Complies with ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.