Description

2-Oxa-6-Azaspiro[3.4]Octane-7-Carboxylic Acid is a high-value, advanced pharmaceutical intermediate featuring a unique spirocyclic scaffold. This compound is critical for medicinal chemistry research and development, particularly in the synthesis of novel bioactive molecules and active pharmaceutical ingredients (APIs). It is primarily sought after by R&D chemists and process development scientists in the pharmaceutical, biotechnology, and fine chemical industries for constructing complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel drug candidates targeting a range of therapeutic areas.
• Medicinal Chemistry Research: Used for structure-activity relationship (SAR) studies and lead optimization in drug discovery programs.
• Spirocyclic Compound Synthesis: Essential for constructing complex spiroheterocyclic frameworks, which are privileged structures in modern drug design.
• Proteolysis Targeting Chimera (PROTAC) Development: Potential application as a linker or component in the design of bifunctional degraders.
• Chemical Biology Probes: Serves as a scaffold for developing tools to study biological pathways and protein function.
• Agrochemical Research: Used in the discovery and development of new active ingredients with novel modes of action.

Basic Information

Product Name	2-Oxa-6-Azaspiro[3.4]Octane-7-Carboxylic Acid
CAS No.	2137470-25-6
Molecular Formula	C7H9NO3
Molecular Weight	155.15 g/mol
Synonyms	7-Carboxy-2-oxa-6-azaspiro[3.4]octane; 2-Oxa-6-azaspiro[3.4]octane-7-carboxylic acid; 6-Azaspiro[3.4]octane-7-carboxylic acid, 2-oxa-; Spiro[3.4]octane-7-carboxylic acid, 2-oxa-6-aza-; 2-Oxa-6-azaspiro[3.4]octane-7-carboxylic acid (CAS 2137470-25-6); 7-Carboxy-2-oxa-6-azaspiro[3.4]oct-6-ene (tautomer); 2-Oxa-6-azaspiro[3.4]octane-7-carboxylate
EINECS	Contact for details

Quality Control

Our 2-Oxa-6-Azaspiro[3.4]Octane-7-Carboxylic Acid is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation via NMR and mass spectrometry, to ensure it meets the high standards required for research and development. Certificates of Analysis (COA) with detailed specifications are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive) and must be kept under an inert atmosphere (e.g., nitrogen or argon) for long-term storage to prevent degradation.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.