Description

tert-Butyl (S)-(4-Oxo-2,3,4,5-tetrahydropyrido[3,2-b][1,4]oxazepin-3-yl)carbamate is a high-purity, chiral pharmaceutical intermediate of significant importance in modern drug discovery. This compound serves as a critical building block for the synthesis of complex molecules targeting neurological and oncological pathways. It is primarily required by research institutions and pharmaceutical companies engaged in the development of novel therapeutic agents, particularly kinase inhibitors and other small-molecule drugs. Our supply ensures consistent quality and reliable availability for critical R&D and scale-up processes.

Application

• Pharmaceutical Intermediate: A key chiral synthon in the research and development of new active pharmaceutical ingredients (APIs).
• Kinase Inhibitor Synthesis: Used as a core scaffold or precursor in the construction of potent and selective kinase inhibitors for oncology targets.
• Neurological Drug Research: Employed in medicinal chemistry programs focused on central nervous system (CNS) disorders.
• Process Chemistry & Scale-Up: Supplied in development and commercial quantities for non-GMP and GMP manufacturing campaigns.
• Academic & Contract Research: Utilized in university labs and CROs (Contract Research Organizations) for exploratory synthesis and hit-to-lead optimization.
• Custom Synthesis Starting Material: Serves as a high-value starting point for custom synthesis and derivatization services.

Basic Information

Product Name	tert-Butyl (S)-(4-Oxo-2,3,4,5-tetrahydropyrido[3,2-b][1,4]oxazepin-3-yl)carbamate
CAS No.	2124262-62-8
Molecular Formula	C15H19N3O4
Molecular Weight	305.33 g/mol
Synonyms	(S)-tert-Butyl (4-oxo-2,3,4,5-tetrahydropyrido[3,2-b][1,4]oxazepin-3-yl)carbamate; tert-Butyl N-[(3S)-4-oxo-2,3,4,5-tetrahydropyrido[3,2-b][1,4]oxazepin-3-yl]carbamate; BOC-Protected (S)-3-Amino-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazepin-5(6H)-one; (S)-3-((tert-Butoxycarbonyl)amino)-3,4-dihydro-2H-pyrido[3,2-b][1,4]oxazepin-5(6H)-one; CAS 2124262-62-8
EINECS	Contact for details

Quality Control

Our tert-Butyl (S)-(4-Oxo-2,3,4,5-tetrahydropyrido[3,2-b][1,4]oxazepin-3-yl)carbamate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing to ensure identity, purity, and consistency, meeting the high standards required for pharmaceutical R&D. Certificates of Analysis (COA) detailing purity (typically by HPLC), chiral purity, and related substances are provided with every shipment. We support development with specifications tailored to your phase-appropriate needs.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at controlled room temperature (15-25°C). This material is moisture-sensitive; keep the container tightly sealed in a dry environment. For long-term storage, consider storage under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Assay (HPLC)	≥97.0%
Chiral Purity (Chiral HPLC)	≥98.0% ee
Related Substances (HPLC)	Total impurities ≤2.0%; Any single unknown impurity ≤0.5%
Residual Solvents (GC)	Complies with ICH Q3C guidelines
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.