Description

3-Chloro-4-Methyl-2-(Methylthio)Phenylboronic Acid Pinacol Ester is a high-purity, synthetically valuable organoboron building block used in advanced cross-coupling reactions. Its core value lies in enabling the efficient and selective construction of complex biaryl and heterocyclic structures, which are critical scaffolds in modern pharmaceutical and agrochemical discovery. This compound is essential for R&D chemists and process development scientists in the life sciences, material science, and specialty chemical industries who require reliable, high-quality intermediates for Suzuki-Miyaura and other palladium-catalyzed couplings.

Application

• Pharmaceutical Intermediate: A key building block for synthesizing active pharmaceutical ingredients (APIs) and drug candidates, particularly those containing complex substituted biphenyl or heteroaryl motifs.
• Agrochemical Synthesis: Used in the research and development of novel herbicides, fungicides, and insecticides where specific chlorinated and methylthio-substituted aromatic systems are required for bioactivity.
• Material Science Research: Employed in the creation of organic electronic materials, such as ligands for catalysts, organic semiconductors, and liquid crystals, where precise molecular architecture is crucial.
• Chemical Biology & Probe Development: Serves as a versatile handle for bioconjugation and the synthesis of molecular probes for studying biological systems.
• Custom Synthesis & Contract Manufacturing: A critical reagent for fine chemical and CDMO (Contract Development and Manufacturing Organization) facilities producing bespoke organic compounds for client projects.
• Academic & Industrial R&D: Fundamental research tool in synthetic organic chemistry laboratories for methodology development and exploring new chemical space.

Basic Information

Product Name	3-Chloro-4-Methyl-2-(Methylthio)Phenylboronic Acid Pinacol Ester
CAS No.	2121512-63-6
Molecular Formula	C14H20BClO2S
Molecular Weight	298.63 g/mol
Synonyms	2-(3-Chloro-4-methyl-2-(methylthio)phenyl)-4,4,5,5-tetramethyl-1,3,2-dioxaborolane; Pinacol [3-Chloro-4-methyl-2-(methylthio)phenyl]boronate; 3-Chloro-4-methyl-2-(methylthio)benzeneboronic acid pinacol ester; (3-Chloro-4-methyl-2-(methylthiophenyl)boronic acid pinacol ester; Boronic acid, B-[3-chloro-4-methyl-2-(methylthio)phenyl]-, 1,1-dimethylethyl ester; CAS 2121512-63-6
EINECS	Contact for details

Quality Control

Every batch of 3-Chloro-4-Methyl-2-(Methylthio)Phenylboronic Acid Pinacol Ester is manufactured under strict quality management protocols. Our products undergo rigorous analytical testing, including HPLC, NMR, and GC-MS, to ensure high chemical purity and identity confirmation. A comprehensive Certificate of Analysis (COA) detailing purity, assay, and impurity profiles is provided with each shipment to guarantee consistency and traceability for your critical R&D and production processes.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed under an inert atmosphere (e.g., nitrogen or argon) after opening to prevent degradation. Keep away from heat and incompatible materials.

Specification

Item	Specification
Appearance	White to off-white crystalline powder or solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥97.0% (Area %)
Assay (NMR)	≥95.0%
Water Content (KF)	≤0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.