Description

Bicyclo[3.1.0]Hexane-3,6-Dicarboxylic Acid, 3-Methyl Ester is a high-value, synthetically derived bicyclic compound featuring a unique strained ring system and ester functionality. This specialized intermediate is critical for advanced organic synthesis, enabling the construction of complex molecular architectures with precise stereochemistry. It is primarily sought after by research and development teams in the pharmaceutical and agrochemical sectors for applications in medicinal chemistry and novel active ingredient discovery.

Application

• Pharmaceutical Intermediate: Serves as a key chiral building block in the synthesis of novel drug candidates, particularly for central nervous system (CNS) and antiviral targets.
• Agrochemical Research: Used in the development of new herbicides, fungicides, and insecticides, leveraging its rigid bicyclic scaffold.
• Material Science Precursor: Acts as a monomer or cross-linking agent for developing specialty polymers with unique thermal and mechanical properties.
• Ligand Synthesis: Employed in the preparation of sophisticated chiral ligands for asymmetric catalysis and metal-organic frameworks (MOFs).
• Academic & Industrial R&D: A valuable tool for methodological studies in organic chemistry, including ring-opening and functionalization reactions.
• Flavor & Fragrance Chemistry: Potential intermediate for synthesizing complex odorants and flavor molecules with bicyclic motifs.

Basic Information

Product Name	Bicyclo[3.1.0]Hexane-3,6-Dicarboxylic Acid, 3-Methyl Ester
CAS No.	2121431-60-3
Molecular Formula	C10H12O4
Molecular Weight	196.20 g/mol
Synonyms	3-Methyl bicyclo[3.1.0]hexane-3,6-dicarboxylate; Bicyclo[3.1.0]hexane-3,6-dicarboxylic acid methyl ester; Methyl 3,6-dicarboxybicyclo[3.1.0]hexane-3-carboxylate; 3-Methyl bicyclo[3.1.0]hexane-3,6-dicarboxylic acid ester; Bicyclo[3.1.0]hexane-3,6-dicarboxylic acid, monomethyl ester; 2121431-60-3; Bicyclo[3.1.0]hexane mono-methyl diester
EINECS	Contact for details

Quality Control

Our Bicyclo[3.1.0]Hexane-3,6-Dicarboxylic Acid, 3-Methyl Ester is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. We provide comprehensive Certificates of Analysis (COA) with each shipment, detailing all critical specifications. Our quality commitment supports applications requiring high-purity intermediates under cGMP and ISO 9001 guidelines.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Keep away from heat, sparks, and open flame. For long-term storage, consider an inert atmosphere to maintain optimal stability.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Total impurities ≤ 3.0%
Residual Solvents (GC)	Meets ICH Q3C guidelines
Water Content (KF)	≤ 0.5% w/w

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.