Description

Cyanine7 Maleimide is a near-infrared fluorescent dye derivative designed for site-specific bioconjugation. This compound is a critical reagent for labeling proteins, antibodies, and other biomolecules via thiol groups, enabling advanced bioimaging and diagnostic applications. It is essential for researchers and developers in the fields of biopharmaceuticals, in vivo imaging, and molecular diagnostics who require high-performance, stable fluorescent probes.

Application

• Site-Specific Protein Labeling: Conjugation to cysteine residues for creating fluorescent antibody-drug conjugates (ADCs) or protein tracking.
• In Vivo Imaging Probes: Development of targeted NIR fluorescent probes for deep-tissue imaging in preclinical research.
• Biomolecule Conjugation: Labeling of peptides, oligonucleotides, or nanoparticles for fluorescence-based assays and detection.
• Diagnostic Assay Development: Key component in lateral flow assays, ELISA, and other immunoassays requiring NIR detection.
• Cell and Tissue Staining: Used in fluorescence microscopy and flow cytometry for cellular analysis.
• Polymer and Material Science: Modification of polymers or surfaces with fluorescent properties for sensor applications.

Basic Information

Product Name	Cyanine7 Maleimide
CAS No.	2120392-49-4
Molecular Formula	C41H45ClN3O3
Molecular Weight	671.27 g/mol
Synonyms	Cy7 Maleimide; Sulfo-Cyanine7 Maleimide (common analog); 2-[(1E,3E)-5-[2,3-Dimethyl-1-(4-sulfobutyl)-3H-indol-1-ium-2-yl]penta-1,3-dien-1-yl]-1-ethyl-3,3-dimethyl-3H-indol-1-ium Maleimide; NIR Dye Maleimide; Maleimide-functionalized Cy7; Near-IR Fluorescent Maleimide Dye
EINECS	Contact for details

Quality Control

Our Cyanine7 Maleimide is produced under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity, NMR for structural confirmation, and mass spectrometry. A Certificate of Analysis (COA) detailing purity, identity, and performance characteristics is provided with every shipment to ensure it meets the stringent requirements for research and diagnostic applications.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under desiccant. This product is hygroscopic (moisture-sensitive) and light-sensitive. Allow the vial to warm to room temperature in a desiccator before opening to minimize moisture absorption.

Specification

Item	Specification
Appearance	Dark green to blue solid
Identification (HPLC/MS)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Absorption (λmax)	~747 nm
Emission (λmax)	~774 nm
Extinction Coefficient	Contact for details
Water Content (KF)	≤ 2.0%
Solubility	Soluble in DMSO, DMF, methanol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.