Description

m-Peg10-Azide is a heterobifunctional polyethylene glycol (PEG) linker featuring a methoxy group at one terminus and a reactive azide group at the other. This compound is essential for creating stable, biocompatible conjugates in advanced bioconjugation and materials science applications. It is primarily utilized by researchers and manufacturers in the pharmaceutical, biotechnology, and diagnostic sectors for developing novel therapeutics, targeted drug delivery systems, and functional biomaterials.

Application

• Bioconjugation and Click Chemistry: The azide terminus enables efficient, site-specific conjugation to alkyne-modified biomolecules (proteins, antibodies, oligonucleotides) via copper-catalyzed or strain-promoted azide-alkyne cycloaddition (CuAAC/SPAAC).
• PEGylation of Therapeutics: Used to modify peptides, proteins, and small molecule drugs to enhance solubility, prolong circulation half-life, and reduce immunogenicity.
• ADC (Antibody-Drug Conjugate) Linker: Serves as a hydrophilic spacer in the construction of ADCs, connecting cytotoxic payloads to monoclonal antibodies to improve stability and therapeutic index.
• Surface Functionalization: Employed to modify nanoparticles, quantum dots, and biosensor surfaces with azide groups for subsequent bio-immobilization.
• Hydrogel and Biomaterial Synthesis: Acts as a cross-linking agent or functional component in the development of PEG-based hydrogels for tissue engineering and controlled release applications.
• Diagnostic Reagent Preparation: Used in the synthesis of fluorescent probes, imaging agents, and other diagnostic tools requiring water-soluble linkers.

Basic Information

Product Name	m-Peg10-Azide
CAS No.	2112738-12-0
Molecular Formula	C23H47N3O11
Molecular Weight	541.64 g/mol
Synonyms	mPEG10-Azide; Methoxy-PEG10-Azide; Azido-PEG10-OMe; α-Methoxy-ω-azido-decaethylene glycol; 2-[2-[2-[2-[2-[2-[2-[2-[2-(2-Methoxyethoxy)ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethoxy]ethyl azide; PEG10 spacer azide; mPEG10-N3
EINECS	Contact for details

Quality Control

Our m-Peg10-Azide is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity and identity confirmation (NMR, IR), to ensure it meets high-grade specifications for research and development. Certificates of Analysis (COA) with detailed chromatographic data are provided to guarantee batch-to-batch consistency and traceability.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at 15-25°C. The product is moisture-sensitive; keep the container tightly sealed under an inert atmosphere (e.g., nitrogen) for long-term storage to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid
Identification (IR)	Conforms to structure
Purity (HPLC)	≥ 95%
Water Content (KF)	≤ 1.0%
Average Molecular Weight	540 - 545 g/mol

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.