Description

Ethyl 6-Benzyl-6-Azaspiro[3.4]Octane-8-Carboxylate is a high-value, nitrogen-containing spirocyclic building block of significant interest in advanced organic synthesis. This compound matters because it provides a rigid, three-dimensional scaffold that is crucial for modulating the physicochemical properties and biological activity of novel molecules. Pharmaceutical research and development teams, particularly in medicinal chemistry, need this intermediate for constructing complex drug candidates targeting central nervous system disorders and other therapeutic areas.

Application

• Pharmaceutical Intermediate: A key building block in the synthesis of novel active pharmaceutical ingredients (APIs), especially for neurological and psychiatric targets.
• Medicinal Chemistry Research: Used in hit-to-lead and lead optimization campaigns to explore structure-activity relationships (SAR) due to its spirocyclic architecture.
• Chemical Biology Probes: Serves as a core structure for developing tool compounds to study biological pathways and protein function.
• Agrochemical Development: Potential intermediate in the research and synthesis of new crop protection agents with novel modes of action.
• Academic & Contract Research: Employed in universities and CROs for methodological development and the discovery of new chemical entities.
• Custom Synthesis: A starting material for contract manufacturing organizations (CMOs) producing bespoke compounds for client projects.

Basic Information

Product Name	Ethyl 6-Benzyl-6-Azaspiro[3.4]Octane-8-Carboxylate
CAS No.	2110507-78-1
Molecular Formula	C16H21NO2
Molecular Weight	259.35 g/mol
Synonyms	Ethyl 6-benzyl-6-azaspiro[3.4]octane-8-carboxylate; 6-Benzyl-6-azaspiro[3.4]octane-8-carboxylic acid ethyl ester; 8-Carbethoxy-6-benzyl-6-azaspiro[3.4]octane; 6-Azaspiro[3.4]octane-8-carboxylic acid, 6-benzyl-, ethyl ester; AZASPIRO OCTANE CARBOXYLATE ETHYL ESTER BENZYL; SCHEMBL21824026; BCP31234; AKOS040757623.
EINECS	Contact for details

Quality Control

Our Ethyl 6-Benzyl-6-Azaspiro[3.4]Octane-8-Carboxylate is manufactured under strict quality management systems. Every batch undergoes rigorous analytical testing, including HPLC, GC, NMR, and mass spectrometry, to ensure identity, purity, and consistency. Certificates of Analysis (COA) with complete batch data are available upon request. We support development and scale-up projects with material produced in compliance with cGMP guidelines where required.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at room temperature (typically 15-25°C). The compound may be hygroscopic; keep the container tightly sealed in a dry environment to prevent moisture absorption.

Specification

Item	Specification
Appearance	White to off-white solid
Identification (IR)	Conforms to structure
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 97.0%
Related Substances (HPLC)	Individual impurity ≤ 1.0%
Residual Solvents (GC)	Complies with ICH Q3C
Water Content (KF)	≤ 0.5%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.