Description

n-[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]-N'-Pyridin-3-Ylurea is a high-purity, advanced pharmaceutical intermediate designed for the synthesis of novel active ingredients. This compound is valued for its unique trifluoromethylpyridine and urea pharmacophores, which are critical for modulating the biological activity and pharmacokinetic properties of target molecules. It is primarily sought after by research institutions and pharmaceutical companies engaged in the development of new therapeutic agents, particularly in oncology and central nervous system (CNS) drug discovery.

Application

• Pharmaceutical Intermediate: A key building block in the research and development of new drug candidates, especially kinase inhibitors.
• Medicinal Chemistry Research: Used in structure-activity relationship (SAR) studies to optimize potency and selectivity of lead compounds.
• Agrochemical Synthesis: Serves as a precursor in the development of advanced crop protection agents with enhanced efficacy.
• Chemical Biology Probes: Utilized in the creation of molecular probes for studying enzyme function and biological pathways.
• Custom Synthesis: Employed in contract research and manufacturing (CRO/CMO) for client-specific molecule assembly.

Basic Information

Item	Detail
Product Name	n-[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]-N'-Pyridin-3-Ylurea
CAS No.	2108876-29-3
Molecular Formula	C13H11F3N4O
Molecular Weight	296.25 g/mol
Synonyms	1-(2-Methyl-6-(trifluoromethyl)pyridin-3-yl)-3-(pyridin-3-yl)urea; 3-Pyridinyl-[2-methyl-6-(trifluoromethyl)-3-pyridinyl]urea; N-(2-Methyl-6-(trifluoromethyl)pyridin-3-yl)-N'-pyridin-3-ylurea; Urea, N-[2-methyl-6-(trifluoromethyl)-3-pyridinyl]-N'-3-pyridinyl-; CAS 2108876-29-3
EINECS	Contact for details

Quality Control

Our n-[2-Methyl-6-(Trifluoromethyl)Pyridin-3-Yl]-N'-Pyridin-3-Ylurea is manufactured under strict quality management systems. Each batch undergoes comprehensive analytical testing, including HPLC for purity and NMR for structural confirmation, to ensure it meets the high standards required for pharmaceutical research. A Certificate of Analysis (COA) detailing all specifications is provided with every shipment to guarantee traceability and compliance.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). Due to its hygroscopic (moisture-sensitive) nature, the container must be kept tightly sealed after each use to prevent degradation from atmospheric moisture.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.