Description

tert-Butyl 2,7-Diazaspiro[4.4]Nonane-2-Carboxylate Oxalate is a high-purity, advanced pharmaceutical intermediate featuring a constrained spirocyclic diaza scaffold. This compound is of significant value for medicinal chemistry research and development, serving as a critical building block for constructing novel drug candidates. It is primarily utilized by pharmaceutical R&D organizations and fine chemical manufacturers focused on developing therapeutics for central nervous system (CNS) disorders, oncology, and other disease areas requiring complex molecular architectures.

Application

• Pharmaceutical Intermediate: A key synthetic precursor in the research and development of novel active pharmaceutical ingredients (APIs), particularly those targeting neurological receptors.
• Medicinal Chemistry Scaffold: Used as a privileged, three-dimensional scaffold in fragment-based drug discovery and lead optimization programs to explore new chemical space.
• Proteolysis Targeting Chimera (PROTAC) Development: Serves as a versatile linker or component in the synthesis of bifunctional PROTAC molecules for targeted protein degradation.
• Chemical Biology Probe Synthesis: Employed in the creation of molecular probes for studying enzyme function and protein-protein interactions within biological systems.
• Contract Research & Manufacturing (CRMO): Supplied to CRMOs and custom synthesis facilities for scale-up projects and the production of non-commercial research quantities.
• Academic Research: Used in university and institutional laboratories for fundamental research in organic synthesis and pharmacology.

Basic Information

Product Name	tert-Butyl 2,7-Diazaspiro[4.4]Nonane-2-Carboxylate Oxalate
CAS No.	2108848-16-2
Molecular Formula	C15H26N2O5
Molecular Weight	314.38 g/mol
Synonyms	2,7-Diazaspiro[4.4]nonane-2-carboxylic acid, 1,1-dimethylethyl ester, oxalate (1:1); tert-Butyl 2,7-diazaspiro[4.4]nonane-2-carboxylate oxalate salt; 2-(tert-Butoxycarbonyl)-2,7-diazaspiro[4.4]nonane oxalate; Boc-2,7-diazaspiro[4.4]nonane oxalate; 2,7-Diazaspiro[4.4]nonane-2-carboxylic acid tert-butyl ester oxalate; 2108848-16-2; UNII-Contact for details
EINECS	Contact for details

Quality Control

Our tert-Butyl 2,7-Diazaspiro[4.4]Nonane-2-Carboxylate Oxalate is manufactured under strict quality management systems. Each batch undergoes rigorous analytical testing, including HPLC for purity, NMR and MS for structural confirmation, and KF titration for moisture content, to ensure it meets the high standards required for pharmaceutical research. Certificates of Analysis (COA) with full traceability are provided for every shipment.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry place at a controlled room temperature (15-25°C). This material is hygroscopic (moisture-sensitive) and must be kept under anhydrous conditions. For long-term storage, consider storing under an inert atmosphere.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.