Description

Ethyl 5-(3,4-Difluorophenyl)-3-Methyl-1H-Pyrrole-2-Carboxylate is a high-value pyrrole derivative, a crucial advanced intermediate in modern organic synthesis. Its molecular structure, featuring a difluorophenyl moiety, makes it a versatile building block for constructing complex molecules with tailored properties. This compound is primarily sought after by pharmaceutical and agrochemical research organizations for the development of novel active ingredients.

Application

• Pharmaceutical Intermediate: A key synthon in the research and development of new drug candidates, particularly in medicinal chemistry programs targeting CNS disorders, inflammation, and metabolic diseases.
• Agrochemical Synthesis: Serves as a core structure for developing new-generation pesticides and herbicides, where the fluorine atoms can enhance biological activity and environmental stability.
• Material Science Research: Used in the synthesis of specialized organic compounds for advanced materials, such as organic semiconductors or ligands for catalysis.
• Chemical Biology Probes: Employed as a scaffold for creating fluorescent tags or molecular probes to study biological processes and enzyme interactions.
• Custom Synthesis & Contract Manufacturing: Supplied to CDMOs (Contract Development and Manufacturing Organizations) for scale-up and production under cGMP conditions for clinical trials.

Basic Information

Product Name	Ethyl 5-(3,4-Difluorophenyl)-3-Methyl-1H-Pyrrole-2-Carboxylate
CAS No.	2106792-88-3
Molecular Formula	C14H13F2NO2
Molecular Weight	265.26 g/mol
Synonyms	Ethyl 5-(3,4-difluorophenyl)-3-methyl-1H-pyrrole-2-carboxylate; 1H-Pyrrole-2-carboxylic acid, 5-(3,4-difluorophenyl)-3-methyl-, ethyl ester; 3-Methyl-5-(3,4-difluorophenyl)-1H-pyrrole-2-carboxylic acid ethyl ester; 2106792-88-3; Ethyl 3-methyl-5-(3,4-difluorophenyl)-1H-pyrrole-2-carboxylate
EINECS	Contact for details

Quality Control

Our Ethyl 5-(3,4-Difluorophenyl)-3-Methyl-1H-Pyrrole-2-Carboxylate is manufactured under strict quality management systems. Every batch undergoes comprehensive analytical testing, including HPLC, GC, NMR, and MS, to ensure identity, purity, and consistency. A detailed Certificate of Analysis (COA) is provided with each shipment, confirming compliance with agreed specifications. We support development and commercial projects requiring ICH stability data and can supply material suitable for cGMP applications.

Storage

Preserve in a tightly closed container, protected from light. Store in a cool, dry, and well-ventilated place at a controlled room temperature (15-25°C). This compound is hygroscopic (moisture-sensitive); therefore, the container must be kept tightly sealed and consideration should be given to storage under an inert atmosphere for long-term preservation.

Specification

Item	Specification
Appearance	White to off-white crystalline powder
Identification (IR)	Conforms to structure
Identification (HPLC)	Retention time matches reference standard
Purity (HPLC)	≥ 98.0%
Water Content (KF)	≤ 0.5%
Residue on Ignition	≤ 0.1%
Heavy Metals	≤ 10 ppm
Single Unknown Impurity (HPLC)	≤ 0.5%
Total Impurities (HPLC)	≤ 2.0%

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.