Description

n-Boc-n-Bis(Peg1-Azide) is a specialized bifunctional linker molecule featuring a Boc-protected amine and two polyethylene glycol (PEG)-spaced azide groups. This compound is engineered for precision in bioconjugation and materials science, enabling controlled, site-specific coupling via click chemistry reactions. It is essential for researchers and manufacturers in pharmaceutical development, proteomics, and advanced polymer synthesis who require reliable, high-purity building blocks for creating complex molecular architectures.

Application

• Bioconjugation and Antibody-Drug Conjugate (ADC) Development: Serves as a key heterobifunctional crosslinker for attaching payloads to proteins, antibodies, or other biomolecules.
• Click Chemistry Scaffolding: The dual azide groups facilitate efficient copper-catalyzed (CuAAC) or strain-promoted (SPAAC) azide-alkyne cycloadditions to create dendrimers or functionalized surfaces.
• Polymer and Materials Functionalization: Used to introduce amine-reactive sites (after Boc deprotection) and clickable handles into hydrogels, nanoparticles, or other polymeric materials.
• Peptide and Protein Modification: Enables the site-specific introduction of PEG chains and subsequent functional groups onto peptides or engineered proteins.
• Chemical Probe Synthesis: A critical intermediate for creating activity-based probes or diagnostic agents used in target identification and validation.
• Solid-Phase Synthesis Support: Can be utilized as a versatile linker on resin for the synthesis of branched or tagged peptide libraries.

Basic Information

Product Name	n-Boc-n-Bis(Peg1-Azide)
CAS No.	2100306-79-2
Molecular Formula	C14H25N7O5
Molecular Weight	371.39 g/mol
Synonyms	1,1'-(2-((tert-Butoxycarbonyl)amino)ethyl)azanediyl)bis(2-azidoethane); 2,2'-(2-((tert-Butoxycarbonyl)amino)ethyl)azanediyl)di(ethan-1-azide); Boc-NH-PEG1-bis-azide; tert-Butyl (2,2'-((2-azidoethyl)azanediyl)bis(ethane-2,1-diyl))dicarbamate; N-Boc-N-bis(PEG1-azide); Boc-protected bis-azide PEG linker; Azide-PEG1-NH-Boc
EINECS	Contact for details

Quality Control

Every batch of n-Boc-n-Bis(Peg1-Azide) is manufactured under strict quality management systems. We employ advanced analytical techniques including HPLC, NMR, and mass spectrometry to ensure identity, purity, and consistency. A comprehensive Certificate of Analysis (COA) detailing all specification results is provided with each shipment to support your quality assurance and regulatory documentation.

Storage

Preserve in a tightly closed container, protected from light. Store at -20°C or below under an inert atmosphere. This compound is hygroscopic (moisture-sensitive) and should be handled in a dry environment to maintain stability.

Specification

Item	Specification
Appearance	Colorless to pale yellow viscous liquid or solid
Identification (HPLC)	Conforms to reference standard
Identification (NMR)	Conforms to structure
Purity (HPLC)	≥ 95.0%
Water Content (KF)	≤ 1.0%
Residual Solvents (GC)	Meets ICH guidelines

Note: Specifications can be tailored. Please contact us for the detailed technical data sheet of a specific grade.